1-Bromo-2,4-dichlorobenzene

Base Information

• Chemical Name: 1-Bromo-2,4-dichlorobenzene
• CAS No.: 1193-72-2
• Molecular Formula: C6H3BrCl2
• Molecular Weight: 225.9
• Hs Code.: 29039990
• European Community (EC) Number: 214-778-6
• NSC Number: 158360
• UNII: 2Z4G4Z84UU
• DSSTox Substance ID: DTXSID10152408
• Nikkaji Number: J31.738A
• Wikidata: Q72465810
• Mol file: 1193-72-2.mol

Synonyms:1-Bromo-2,4-dichlorobenzene;1193-72-2;2,4-dichlorobromobenzene;Benzene, 1-bromo-2,4-dichloro-;2,4-dichloro-1-bromobenzene;EINECS 214-778-6;MFCD00018333;NSC-158360;1-bromo-2,4-dichloro-benzene;Clc1cc(Cl)ccc1Br;NSC158360;2,4-dichlorobromobenze;2,4-dichloro-bromobenzene;2,4-Dichloro Bromo Benzene;bromo(2-)-4-dichlorobenzene;4-Bromo-1,3-dichlorobenzene;2Z4G4Z84UU;SCHEMBL1389468;ISHYFWKKWKXXPL-UHFFFAOYSA-;DTXSID10152408;1-Bromo-2,4-dichlorobenzene, 97%;AKOS005265552;CS-W013035;GS-3169;NSC 158360;PB47597;BP-11090;SY023022;AM20060135;B2187;FT-0610056;EN300-78159;F11413;W-108515

Chemical Property of 1-Bromo-2,4-dichlorobenzene

Chemical Property:

• Appearance/Colour: white to light yellow crystal powder
• Vapor Pressure: 0.0714mmHg at 25°C
• Melting Point: 26-30 °C(lit.)
• Refractive Index: 1.59
• Boiling Point: 236.8 °C at 760 mmHg
• Flash Point: 106.7 °C
• PSA: 0.00000
• Density: 1.744 g/cm³
• LogP: 3.75590
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Water Solubility.: Slightly soluble in water.
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 223.87952
• Heavy Atom Count: 9
• Complexity: 97.1

Purity/Quality:

98% ^*data from raw suppliers

2,4-dichlorobromobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)Cl)Br
• Uses: 1-Bromo-2,4-dichlorobenzene is used to produce 2,4,4'-trichloro-biphenyl. This reaction will need aq. Na2CO3 and solvents dioxane, ethanol. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.

Technology Process of 1-Bromo-2,4-dichlorobenzene

There total 10 articles about 1-Bromo-2,4-dichlorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

1,3-Dichlorobenzene (541-73-1) → 1-bromo-2,4-dichlorobenzene (1193-72-2)

Guidance literature:

With bromine; iron(III) chloride;

Reference yield: 97.0%

→ 1-bromo-2,4-dichlorobenzene (1193-72-2)

Guidance literature:

With bromine; dibromoisocyanuric acid; In dichloromethane; at 20 ℃; for 24h; UV-irradiation;

Reference yield: 72.0%

→ 1-bromo-2,4-dichlorobenzene (1193-72-2) + 1,2,4-Trichlorobenzene (120-82-1,63697-18-7)

Guidance literature:

With Bromotrichloromethane; trichloroisocyanuric acid; bromine; at 10 - 120 ℃; for 0.5h; Photolysis;

upstream raw materials:

2,4-Dichloro-benzenediazonium

5-bromo-2,4-dichloro-aniline

2,4-Dichloroaniline

methanesulfonyl chloride

Downstream raw materials:

2,4-dichlorophenol

2-Bromo-5-chlorophenol

1-bromo-2,4-dichloro-3,5-dinitro-benzene

PCB 7

Refernces

• 1、 Phuc Tran, Dat,Nomoto, Akihiro,Mita, Soichiro,Dong, Chun-ping,Kodama, Shintaro,Mizuno, Takumi,Ogawa, Akiya. "Metal- and base-free synthesis of aryl bromides from arylhydrazines". supporting information. . Retrieved 2020/05/08.
• 2、 -. "PROCESS FOR THE PREPARATION OF ORGANIC HALIDES". Paragraph 00143. . Retrieved 2017/08/01.