5-[(prop-2-yn-1-yloxy)methyl]-3-[2-(trifluoromethyl)phenyl]-1,3-oxazolidin-2-one

Base Information

Chemical Name:5-[(prop-2-yn-1-yloxy)methyl]-3-[2-(trifluoromethyl)phenyl]-1,3-oxazolidin-2-one
CAS No.:23598-53-0
Molecular Formula:C₁₄H₁₂F₃NO₃
Molecular Weight:299.249
Hs Code.:

Synonyms:2-Oxazolidinone,5-[(2-propynyloxy)methyl]-3-(a,a,a-trifluoro-m-tolyl)- (8CI); 2-Oxazolidinone,5-[(2-propynyloxy)methyl]-3-[(trifluoromethyl)phenyl]- (9CI)

Suppliers and Price of 5-[(prop-2-yn-1-yloxy)methyl]-3-[2-(trifluoromethyl)phenyl]-1,3-oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[(prop-2-yn-1-yloxy)methyl]-3-[2-(trifluoromethyl)phenyl]-1,3-oxazolidin-2-one

Chemical Property:

Vapor Pressure:1.97E-05mmHg at 25°C
Boiling Point:362.2°Cat760mmHg
Flash Point:172.8°C
Density:1.325g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-[(prop-2-yn-1-yloxy)methyl]-3-[2-(trifluoromethyl)phenyl]-1,3-oxazolidin-2-one

There total 4 articles about 5-[(prop-2-yn-1-yloxy)methyl]-3-[2-(trifluoromethyl)phenyl]-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-44-5
phosgene

: 23452-72-4
1-prop-2-ynyloxy-3-(3-trifluoromethyl-anilino)-propan-2-ol

: 23598-53-0
5-prop-2-ynyloxymethyl-3-(3-trifluoromethyl-phenyl)-oxazolidin-2-one

Guidance literature:: With potassium carbonate; In toluene; at 40 ℃; for 3h;

Reference yield:

: 18180-30-8
prop-2-ynyloxymethyl-oxirane

: 23598-53-0
5-prop-2-ynyloxymethyl-3-(3-trifluoromethyl-phenyl)-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 2 h / Heating

2: K₂CO₃ / toluene / 3 h / 40 °C

With potassium carbonate; In methanol; toluene;