2-(naphthalen-1-yl)-2,3-dihydro-1,3-benzothiazole

Base Information

• Chemical Name: 2-(naphthalen-1-yl)-2,3-dihydro-1,3-benzothiazole
• CAS No.: 56048-67-0
• Molecular Formula: C17H13 N S
• Molecular Weight: 263.3568
• Mol file: 56048-67-0.mol

Synonyms:2-(1-Naphthyl)benzothiazoline;NSC 149797

Chemical Property of 2-(naphthalen-1-yl)-2,3-dihydro-1,3-benzothiazole

Chemical Property:

• Vapor Pressure: 7.25E-09mmHg at 25°C
• Boiling Point: 466.1°Cat760mmHg
• Flash Point: 235.7°C
• Density: 1.24g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(naphthalen-1-yl)-2,3-dihydro-1,3-benzothiazole

There total 2 articles about 2-(naphthalen-1-yl)-2,3-dihydro-1,3-benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-naphthaldehyde (66-77-3) + 2-amino-benzenethiol (137-07-5) → 2-(1-naphthyl)benzothiazoline (56048-67-0)

Guidance literature:

In ethanol; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ol901762g

Reference yield:

→ 2-(1-naphthyl)benzothiazoline (56048-67-0)

Guidance literature:

Aminothiophenol, entspr.Aldehyd;

Reference yield: 92.0%

2-(1-naphthyl)benzothiazoline (56048-67-0) → 2-(1-naphthyl)benzothiazole (56048-50-1)

Guidance literature:

With tris(pentafluorophenyl)borate; In para-xylene; at 150 ℃; for 22h; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201606177

upstream raw materials:

1-naphthaldehyde

2-amino-benzenethiol

Downstream raw materials:

4-methoxy-N-(naphthalen-1-yl-methyl)aniline

2-(1-naphthyl)benzothiazole

Refernces

• 1、 Zhu, Chen,Aklyama, Takahlko. "Benzothiazoline: highly efficient reducing agent for the enantioselective organocatalytic transfer hydrogenation of ketimines". supporting information; experimental part. p. 4180 - 4183. Retrieved 2009/12/30.