1-(3-Aminophenyl)pyrrolidin-2-one

Base Information

Chemical Name:1-(3-Aminophenyl)pyrrolidin-2-one
CAS No.:31992-43-5
Molecular Formula:C10H12 N2 O
Molecular Weight:176.218
Hs Code.:2933790090
European Community (EC) Number:828-616-2
DSSTox Substance ID:DTXSID60350593
Wikidata:Q82126624
Mol file:31992-43-5.mol

Synonyms:1-(3-aminophenyl)pyrrolidin-2-one;31992-43-5;1-(3-Amino-phenyl)-pyrrolidin-2-one;1-(3-aminophenyl)-2-pyrrolidinone;2-Pyrrolidinone, 1-(3-aminophenyl)-;MFCD00468694;Oprea1_818804;SCHEMBL519856;DTXSID60350593;STK500352;AKOS000199749;BB 0256553;CS-0208335;FT-0677641;EN300-13966;1-(3-Aminophenyl)pyrrolidin-2-one, AldrichCPR;3Y-0809;SR-01000509899;J-018593;SR-01000509899-1;Z96092030;F2148-0021

Suppliers and Price of 1-(3-Aminophenyl)pyrrolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(3-Aminophenyl)pyrrolidin-2-one
500mg
$ 75.00

Sigma-Aldrich
1-(3-Aminophenyl)pyrrolidin-2-one Aldrich
1g
$ 215.00

Matrix Scientific
1-(3-Amino-phenyl)-pyrrolidin-2-one
1g
$ 69.00

Matrix Scientific
1-(3-Amino-phenyl)-pyrrolidin-2-one
500mg
$ 42.00

Matrix Scientific
1-(3-Amino-phenyl)-pyrrolidin-2-one
5g
$ 245.00

Chemenu
1-(3-Amino-phenyl)-pyrrolidin-2-one 95%
10g
$ 556.00

Chemenu
1-(3-Amino-phenyl)-pyrrolidin-2-one 95%
5g
$ 351.00

ChemBridge Corporation
1-(3-aminophenyl)pyrrolidin-2-one 95%
10 g
$ 179.20

Biosynth Carbosynth
1-(3-Aminophenyl)pyrrolidin-2-one
250 mg
$ 85.00

Biosynth Carbosynth
1-(3-Aminophenyl)pyrrolidin-2-one
500 mg
$ 150.00

Total 20 raw suppliers

Chemical Property of 1-(3-Aminophenyl)pyrrolidin-2-one

Chemical Property:

Vapor Pressure:8.34E-09mmHg at 25°C
Melting Point:105-107 °C(Solv: benzene (71-43-2))
Boiling Point:464.5°C at 760 mmHg
PKA:4.22±0.10(Predicted)
Flash Point:234.7°C
PSA：46.33000
Density:1.234g/cm³
LogP:2.04180
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:176.094963011
Heavy Atom Count:13
Complexity:205

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Aminophenyl)pyrrolidin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1)C2=CC=CC(=C2)N

Technology Process of 1-(3-Aminophenyl)pyrrolidin-2-one

There total 5 articles about 1-(3-Aminophenyl)pyrrolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 61372-79-0
1-(3-nitrophenyl)-2-oxotetrahydropyrrole

: 31992-43-5
1-(3-aminophenyl)pyrrolidin-2-one

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 2h; under 2585.81 Torr;

Reference yield:

: 585-79-5
m-nitrobromobenzene

: 31992-43-5
1-(3-aminophenyl)pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; trans-1,2-cyclohexanediamine / copper(l) iodide / 1,4-dioxane / 24 h / 110 °C

2: hydrogen / palladium 10% on activated carbon / methanol / 17 h / 20 °C

With hydrogen; potassium carbonate; trans-1,2-cyclohexanediamine; copper(l) iodide; palladium 10% on activated carbon; In 1,4-dioxane; methanol;

Reference yield:

: 99-09-2
3-nitro-aniline

: 31992-43-5
1-(3-aminophenyl)pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: disodium hydrogen phosphate monohydrate / chloroform / 15 h / 25 °C

1.2: 15 h / 25 °C

2.1: hydrogen; palladium on activated charcoal / ethyl acetate / 25 °C

With disodium hydrogen phosphate monohydrate; palladium on activated charcoal; hydrogen; In chloroform; ethyl acetate;
DOI:10.1016/j.bmc.2018.07.042