3,5-Hexadiene-1,5-diol, 1-benzoate, (3E)-

Base Information

Chemical Name:3,5-Hexadiene-1,5-diol, 1-benzoate, (3E)-
CAS No.:500770-37-6
Molecular Formula:C13H14O3
Molecular Weight:218.252
Hs Code.:

Synonyms:

Suppliers and Price of 3,5-Hexadiene-1,5-diol, 1-benzoate, (3E)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,5-Hexadiene-1,5-diol, 1-benzoate, (3E)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,5-Hexadiene-1,5-diol, 1-benzoate, (3E)-

There total 1 articles about 3,5-Hexadiene-1,5-diol, 1-benzoate, (3E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 3068-00-6,6810-31-7
D,L-1,2,4-butanetriol

: 98-88-4
benzoyl chloride

: 1439-36-7
1-triphenylphosphoranylidene-2-propanone

: 500770-37-6
Benzoic acid (E)-5-hydroxy-hexa-3,5-dienyl ester

Guidance literature:: D,L-1,2,4-butanetriol; With sodium periodate; In water; at 0 ℃; for 0.0833333h;

1-triphenylphosphoranylidene-2-propanone; With sodium acetate; In chloroform; water; at 20 ℃; for 12h;

benzoyl chloride; With triethylamine; In dichloromethane; at 20 ℃; for 12h;
DOI:10.7164/antibiotics.55.1076

Reference yield: 79.0%

: 814-49-3
diethyl chlorophosphate

: 500770-37-6
Benzoic acid (E)-5-hydroxy-hexa-3,5-dienyl ester

: 500770-25-2
Benzoic acid (E)-5-(diethoxy-phosphoryloxy)-hexa-3,5-dienyl ester

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃; for 0.166667h;
DOI:10.7164/antibiotics.55.1076

Reference yield:

: 500770-37-6
Benzoic acid (E)-5-hydroxy-hexa-3,5-dienyl ester

: 150829-94-0
(+/-)-UCE6

Guidance literature:: Multi-step reaction with 14 steps

1.1: 79 percent / LiN(TMS)2 / tetrahydrofuran / 0.17 h / -78 - 20 °C

2.1: 64 percent / BF₃*Et₂O / toluene / 12 h / 20 °C

3.1: LiN(TMS)2 / tetrahydrofuran / 0.08 h / 20 °C

3.2: 68 percent / 30 percent H₂O₂; aq. NaHCO₃ / CH₂Cl₂ / 36 h / 20 °C

4.1: 81 percent / NaBH₄; CeCl₃*7H₂O; NaOEt / ethanol / 12 h / 0 - 40 °C

5.1: 86 percent / (COCl)2; Et₃N / dimethylsulfoxide; CH₂Cl₂ / 1 h / -78 - 20 °C

6.1: 81 percent / tetrahydrofuran / 1 h / -10 °C

7.1: 84 percent / o-iodoxybenzoic acid / toluene; dimethylsulfoxide / 3 h / 20 °C

8.1: 85 percent / diisopinocampheylchloroborane; Et₃N / CH₂Cl₂ / 4 h / -78 - 20 °C

9.1: 75 percent / TMSOTf / CH₂Cl₂; cyclohexane / 2 h / 20 °C

10.1: 75 percent / TMSOTf / CH₂Cl₂ / 1 h / -78 - 0 °C

11.1: LiN(TMS)2 / tetrahydrofuran / 2 h / -78 - 60 °C

11.2: 64 percent / BnOMe / Pd-C / toluene / 15 h / 110 °C

12.1: 85 percent / t-BuOK / H₂O; 2-methyl-propan-2-ol / 0.25 h / 60 °C

13.1: 90 percent / H₂ / Pd(OH)2-C / dioxane / 2 h / 20 °C

14.1: 76 percent / LiBF₄ / tetrahydrofuran; acetonitrile; H₂O / 72 h / 70 °C

With sodium tetrahydroborate; lithium tetrafluoroborate; cerium(III) chloride; oxalyl dichloride; trimethylsilyl trifluoromethanesulfonate; diisopinocamphenylchloroborane; boron trifluoride diethyl etherate; potassium tert-butylate; hydrogen; sodium ethanolate; triethylamine; lithium hexamethyldisilazane; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; palladium hydroxide - carbon; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; cyclohexane; water; dimethyl sulfoxide; toluene; acetonitrile; tert-butyl alcohol; 6.1: Grignard reaction;
DOI:10.7164/antibiotics.55.1076