Glycine, N-[3-[[3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl][(2-nitrophenyl) sulfonyl]amino]propyl]-N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Glycine, N-[3-[[3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl][(2-nitrophenyl) sulfonyl]amino]propyl]-N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester
CAS No.:501097-20-7
Molecular Formula:C44H49N5O11S2
Molecular Weight:888.032
Hs Code.:

Glycine,
N-[3-[[3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl][(2-nitrophenyl)
sulfonyl]amino]propyl]-N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl
ester

Synonyms:

Suppliers and Price of Glycine, N-[3-[[3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl][(2-nitrophenyl) sulfonyl]amino]propyl]-N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Glycine, N-[3-[[3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl][(2-nitrophenyl) sulfonyl]amino]propyl]-N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Glycine, N-[3-[[3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl][(2-nitrophenyl) sulfonyl]amino]propyl]-N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester

There total 6 articles about Glycine, N-[3-[[3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl][(2-nitrophenyl) sulfonyl]amino]propyl]-N-[(2-nitrophenyl)sulfonyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 501097-15-0
N-(4-monomethoxytrityl)-3-bromopropylamine

: 501097-19-4
{(2-nitro-benzenesulfonyl)-[3-(2-nitro-benzenesulfonylamino)-propyl]-amino}-acetic acid tert-butyl ester

: [2-tert-butoxy-1-(2-nitro-benzenesulfonyl)-1,4,5,6-tetrahydro-pyridin-3-yl]-(2-nitro-phenyl)-amine

: 501097-20-7
[{3-[(3-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-propyl)-(2-nitro-benzenesulfonyl)-amino]-propyl}-(2-nitro-benzenesulfonyl)-amino]-acetic acid tert-butyl ester

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 18h;
DOI:10.1016/S0223-5234(02)01380-6

Reference yield:

: 1694-92-4
2-Nitrobenzenesulfonyl chloride

: 501097-20-7
[{3-[(3-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-propyl)-(2-nitro-benzenesulfonyl)-amino]-propyl}-(2-nitro-benzenesulfonyl)-amino]-acetic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent / NMM / CH₂Cl₂ / 2 h / 20 °C

2: 95 percent / Cs₂CO₃ / dimethylformamide / 18 h / 20 °C

3: 92 percent / CH₂Cl₂ / 2 h

4: 77 percent / NMM / CH₂Cl₂ / 2 h / 20 °C

5: 50 percent / Cs₂CO₃ / dimethylformamide / 18 h / 20 °C

With 4-methyl-morpholine; caesium carbonate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0223-5234(02)01380-6

Reference yield:

: 14470-28-1
mono-4-methoxytrityl chloride

: 501097-20-7
[{3-[(3-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-propyl)-(2-nitro-benzenesulfonyl)-amino]-propyl}-(2-nitro-benzenesulfonyl)-amino]-acetic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / TEA / CH₂Cl₂ / 0 h / 20 °C

2: 50 percent / Cs₂CO₃ / dimethylformamide / 18 h / 20 °C

With TEA; caesium carbonate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0223-5234(02)01380-6