Dodecanoic acid, 3,11-bis(methoxymethoxy)-4,6,8,10-tetramethyl-12-(phenylmethoxy)-, (3S,4S,6S,8R,10S,11R)-

Base Information

Chemical Name:Dodecanoic acid, 3,11-bis(methoxymethoxy)-4,6,8,10-tetramethyl-12-(phenylmethoxy)-, (3S,4S,6S,8R,10S,11R)-
CAS No.:501419-36-9
Molecular Formula:C27H46O7
Molecular Weight:482.658
Hs Code.:

Synonyms:

Suppliers and Price of Dodecanoic acid, 3,11-bis(methoxymethoxy)-4,6,8,10-tetramethyl-12-(phenylmethoxy)-, (3S,4S,6S,8R,10S,11R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Dodecanoic acid, 3,11-bis(methoxymethoxy)-4,6,8,10-tetramethyl-12-(phenylmethoxy)-, (3S,4S,6S,8R,10S,11R)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Dodecanoic acid, 3,11-bis(methoxymethoxy)-4,6,8,10-tetramethyl-12-(phenylmethoxy)-, (3S,4S,6S,8R,10S,11R)-

There total 26 articles about Dodecanoic acid, 3,11-bis(methoxymethoxy)-4,6,8,10-tetramethyl-12-(phenylmethoxy)-, (3S,4S,6S,8R,10S,11R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 501419-35-8
C₂₇H₄₆O₆

: 501419-36-9
C₂₇H₄₆O₇

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In water; tert-butyl alcohol; at 0 ℃; for 1h;
DOI:10.1021/ja028941u

Reference yield:

: 501419-25-6
(+)-(2S,3R)-4-benzyloxy-3-(tert-butyldimethylsiloxy)-2-methylbutan-1-ol

: 501419-36-9
C₂₇H₄₆O₇

Guidance literature:: Multi-step reaction with 16 steps

1.1: 96 percent / triphenylphosphine; iodine; imidazole / acetonitrile; diethyl ether / 20 °C

2.1: LiCl; diisopropylamine; n-butyllithium / tetrahydrofuran; petroleum ether / 1.33 h / -78 - 20 °C

2.2: 93 percent / tetrahydrofuran; various solvent(s) / 40 h / 0 °C

3.1: 93 percent / diisopropylamine; n-butyllithium; borane-ammonium complex / tetrahydrofuran; petroleum ether / 2.17 h / 0 - 20 °C

4.1: 95 percent / triphenylphosphine; imidazole; iodine / diethyl ether; acetonitrile / 0.17 h / 20 °C

5.1: tert-butyllithium; ZnCl₂ / diethyl ether; petroleum ether / 1 h / 20 °C

5.2: 58 percent / Pd(PPh₃)4 / diethyl ether; various solvent(s) / 16 h

6.1: 87 percent / TBAF / tetrahydrofuran / 20 h / 20 °C

7.1: 86 percent / H₂ / Rh[(nbd)dppb]BF₄ / CH₂Cl₂ / 4 h / 36201.3 Torr

8.1: 100 percent / 2,6-lutidine / CH₂Cl₂ / 1 h / 20 °C

9.1: 93 percent / DDQ / CH₂Cl₂ / 1 h / 20 °C / pH 7

10.1: triethylamine / CH₂Cl₂ / 1.5 h / 20 °C

11.1: HF / acetonitrile / 3 h / 20 °C

12.1: 98 percent / potassium carbonate / methanol / 0.75 h

13.1: 92 percent / lithium perchlorate / acetonitrile / 24 h / 70 °C

14.1: 81 percent / diisopropylethylamine / CH₂Cl₂ / 28 h / 20 °C

15.1: DIBAL-H / CH₂Cl₂; petroleum ether / 1 h / -78 °C

16.1: 2-methyl-2-butene; NaH₂PO₄; NaClO₂ / H₂O; 2-methyl-propan-2-ol / 1 h / 0 °C

With 1H-imidazole; 2,6-dimethylpyridine; sodium chlorite; sodium dihydrogenphosphate; n-butyllithium; 2-methyl-but-2-ene; hydrogen fluoride; tetrabutyl ammonium fluoride; hydrogen; iodine; tert.-butyl lithium; lithium perchlorate; diisobutylaluminium hydride; potassium carbonate; triethylamine; diisopropylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium chloride; zinc(II) chloride; {(1,4-bis(diphenylphosphino)butane)Rh(norbornadiene)}BF₄; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; acetonitrile; Petroleum ether; tert-butyl alcohol; 2.1: Myer's alkylation / 5.2: Negishi coupling;
DOI:10.1021/ja028941u

Reference yield:

: 501419-24-5
4-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-butyric acid methyl ester

: 501419-36-9
C₂₇H₄₆O₇

Guidance literature:: Multi-step reaction with 17 steps

1.1: 94 percent / DIBAL-H / CH₂Cl₂ / 1.25 h / -78 - 0 °C

2.1: 96 percent / triphenylphosphine; iodine; imidazole / acetonitrile; diethyl ether / 20 °C

3.1: LiCl; diisopropylamine; n-butyllithium / tetrahydrofuran; petroleum ether / 1.33 h / -78 - 20 °C

3.2: 93 percent / tetrahydrofuran; various solvent(s) / 40 h / 0 °C

4.1: 93 percent / diisopropylamine; n-butyllithium; borane-ammonium complex / tetrahydrofuran; petroleum ether / 2.17 h / 0 - 20 °C

5.1: 95 percent / triphenylphosphine; imidazole; iodine / diethyl ether; acetonitrile / 0.17 h / 20 °C

6.1: tert-butyllithium; ZnCl₂ / diethyl ether; petroleum ether / 1 h / 20 °C

6.2: 58 percent / Pd(PPh₃)4 / diethyl ether; various solvent(s) / 16 h

7.1: 87 percent / TBAF / tetrahydrofuran / 20 h / 20 °C

8.1: 86 percent / H₂ / Rh[(nbd)dppb]BF₄ / CH₂Cl₂ / 4 h / 36201.3 Torr

9.1: 100 percent / 2,6-lutidine / CH₂Cl₂ / 1 h / 20 °C

10.1: 93 percent / DDQ / CH₂Cl₂ / 1 h / 20 °C / pH 7

11.1: triethylamine / CH₂Cl₂ / 1.5 h / 20 °C

12.1: HF / acetonitrile / 3 h / 20 °C

13.1: 98 percent / potassium carbonate / methanol / 0.75 h

14.1: 92 percent / lithium perchlorate / acetonitrile / 24 h / 70 °C

15.1: 81 percent / diisopropylethylamine / CH₂Cl₂ / 28 h / 20 °C

16.1: DIBAL-H / CH₂Cl₂; petroleum ether / 1 h / -78 °C

17.1: 2-methyl-2-butene; NaH₂PO₄; NaClO₂ / H₂O; 2-methyl-propan-2-ol / 1 h / 0 °C

With 1H-imidazole; 2,6-dimethylpyridine; sodium chlorite; sodium dihydrogenphosphate; n-butyllithium; 2-methyl-but-2-ene; hydrogen fluoride; tetrabutyl ammonium fluoride; hydrogen; iodine; tert.-butyl lithium; lithium perchlorate; diisobutylaluminium hydride; potassium carbonate; triethylamine; diisopropylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium chloride; zinc(II) chloride; {(1,4-bis(diphenylphosphino)butane)Rh(norbornadiene)}BF₄; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; acetonitrile; Petroleum ether; tert-butyl alcohol; 3.1: Myer's alkylation / 6.2: Negishi coupling;
DOI:10.1021/ja028941u