501419-25-6

Upstream product

• 642993-67-7 (2R,3R)-4-(benzyloxy)-3-[(tert-butyldimethylsilyl)oxy]-2-methylbutanal 
• 112638-29-6 (2R,3R)-4-Benzyloxy-3-hydroxy-2-methyl-butyric acid methyl ester 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 60656-87-3 benzyloxyacetoaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 642993-64-4 (-)-phenyl (2R,3R)-4-benzyloxy-3-hydroxy-2-methylbutanoate 
• 642993-51-9 1-(1H-benzotriazol-1-yl)-2-benzyloxyethan-1-one 
• 426833-07-0 (-)-(2R,3R)-4-benzyloxy-3-hydroxy-2-methyl-1-phenyl-butan-1-one 
• 426833-01-4 4-benzyloxy-2-methyl-1-phenylbutane-1,3-dione 
• 30379-55-6 benzyloxyacetic acid 
• 643727-57-5 (-)-phenyl (2R,3R)-4-benzyloxy-3-(tert-butyldimethylsiloxy)-2-methylbutyrate 
• 501419-24-5 4-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-butyric acid methyl ester 

Downstream Products

• 501419-03-0 3R-tert-butyldimethylsiloxy-2R-methyl-4-benzyloxy-1-iodobutane 
• 642993-72-4 (+)-(2S,3R,4S,5R)-6-benzyloxy-5-(tert-butyldimethylsiloxy)-3-hydroxy-2,4-dimethyl-N-methoxy-N-methylhexanamide 
• 643727-59-7 (+)-(2S,3R,4S,5R)-6-benzyloxy-3,5-bis(tert-butyldimethylsiloxy)-2,4-dimethylhexanal 
• 643727-58-6 (+)-(2S,3R,4S,5R)-6-benzyloxy-3,5-bis(tert-butyldimethylsiloxy)-2,4-dimethyl-N-methoxy-N-methylhexanamide 
• 642993-74-6 2-[(1S,2R,3S,4R)-5-Benzyloxy-2,4-bis-(tert-butyl-dimethyl-silanyloxy)-1,3-dimethyl-pentyl]-[1,3]dithiane 
• 642993-70-2 (S)-4-Benzyl-3-[(2S,3R,4S,5R)-6-benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,4-dimethyl-hexanoyl]-oxazolidin-2-one 
• 1126105-93-8 (5R,6S)-5-(benzyloxymethyl)-2,2,3,3,6,9,9,10,10-nonamethyl-4,8-dioxa-3,9-disilaundecane 
• 7184-60-3 borrelidin 
• 501419-08-5 3S,5,7S,9S-tetramethyl-11-benzyloxy-1-paramethoxybenzyloxy-2R,10R-bis-(tert-butyldimethylsiloxy)-4E-undecene 
• 501419-27-8 3S,5,7S,9S-tetramethyl-11-benzyloxy-1-paramethoxybenzyloxy-2R,10R-dihydroxy-4E-undecene 
• 501419-10-9 2R,10R-hydroxy-3S,5S,7R,9S-tetramethyl-11-benzyloxy-1-paramethoxybenzyloxy-undecene 
• 501419-04-1 6-benzyloxy-5R-(tert-butyl-dimethyl-silanyloxy)-2S,4S-dimethyl-hexanoic acid (2S-hydroxy-1S-methyl-2-phenyl-ethyl)-methyl-amide 
• 501419-06-3 5R-tert-butyldimethylsiloxy-2S,4S-dimethyl-6-benzyloxy-1-iodohexane 
• 501419-26-7 5R-tert-butyldimethylsiloxy-2S,4S-dimethyl-6-benzyloxy-hexanol 

Relevant academic research and scientific papers

Synthesis of a 35-member stereoisomer library of bistramide A: Evaluation of effects on actin state, cell cycle and tumor cell growth

Synthesis and preliminary biological evaluation of a 35-member library of bistramide A stereoisomers are reported. All eight stereoisomers of the C1-C13 tetrahydropyran fragment of the molecule were prepared utilizing crotylsilane reagents 9 and 10 in our

Synthesis of the C14-C25 Subunit of Bafilomycin A1

The enantioselective synthesis of the C14-C25 subunit of bafilomycin A 1, was realized in a convergent route. The sequence involves two dynamic kinetic resolution steps of 2-alkyl 1,3-diketones that use optically active ruthenium complexes, an

Enantioselective monoreduction of 2-alkyl 1,3-diketones using chiral ruthenium catalysts. Synthesis of the C14-C25 fragment of bafilomycin A 1

The enantioselective monoreduction of 2-alkyl 1,3-diketones by dynamic kinetic resolution using optically active ruthenium catalysts allowed the preparation of the C14-C25 fragment of bafilomycin A1.

Enantioselective total synthesis of borrelidin

The first total synthesis of the natural product borrelidin is described. The propionate fragment of the molecule was concisely synthesized through catalytic enantioselective reductive aldol reactions, a catalytic Negishi coupling, and a catalytic directed hydrogenation. The propionate segment was then fused to the vinyl iodide fragment through a catalytic Sonogashira coupling. Subsequent catalytic hydrostannylation and catalytic cyanation allowed access to the target structure. Copyright