10-(4-methylphenyl)-10-oxo-decanoic acid

Base Information

• Chemical Name: 10-(4-methylphenyl)-10-oxo-decanoic acid
• CAS No.: 6296-37-3
• Molecular Formula: C17H24 O3
• Molecular Weight: 276.37
• Mol file: 6296-37-3.mol

Synonyms:Nonanoicacid, 9-p-toluoyl- (6CI,8CI); NSC 49897

Chemical Property of 10-(4-methylphenyl)-10-oxo-decanoic acid

Chemical Property:

• Vapor Pressure: 7.58E-09mmHg at 25°C
• Boiling Point: 449°C at 760 mmHg
• PKA: 4.78±0.10(Predicted)
• Flash Point: 239.5°C
• PSA: 54.37000
• Density: 1.047g/cm³
• LogP: 4.38310

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 10-(4-methylphenyl)-10-oxo-decanoic acid

There total 4 articles about 10-(4-methylphenyl)-10-oxo-decanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 10-(4-methylphenyl)-10-oxodecanoate → 10-oxo-10-p-tolyl-decanoic acid (6296-37-3)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 4h;

Reference yield:

methyl 10-chloro-10-oxodecanoate (14065-32-8) → 10-oxo-10-p-tolyl-decanoic acid (6296-37-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminum (III) chloride / dichloromethane / 3 h / 20 °C / Cooling with ice

2: sodium hydroxide; water / methanol; tetrahydrofuran / 4 h / 20 °C

With aluminum (III) chloride; water; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

toluene (108-88-3,15644-74-3,16713-13-6) → 10-oxo-10-p-tolyl-decanoic acid (6296-37-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminum (III) chloride / dichloromethane / 3 h / 20 °C / Cooling with ice

2: sodium hydroxide; water / methanol; tetrahydrofuran / 4 h / 20 °C

With aluminum (III) chloride; water; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane;

upstream raw materials:

methyl 10-chloro-10-oxodecanoate

toluene

Downstream raw materials:

10-(4-methylphenyl)decanoic acid

10-(3-amino-4-methyl-phenyl)-10-oxo-decanoic acid