6-Amino-1-methyluracil

Base Information

Chemical Name:6-Amino-1-methyluracil
CAS No.:2434-53-9
Molecular Formula:C5 H7 N3 O2
Molecular Weight:141.129
Hs Code.:29335990
European Community (EC) Number:219-422-3
NSC Number:7369
DSSTox Substance ID:DTXSID30179076
Nikkaji Number:J216.075G
Wikidata:Q63408603
ChEMBL ID:CHEMBL89725
Mol file:2434-53-9.mol

Synonyms:6-Amino-1-methyluracil;2434-53-9;6-amino-1-methylpyrimidine-2,4(1H,3H)-dione;1-methyl-6-Aminouracil;6-amino-1-methylpyrimidine-2,4-dione;MFCD00075366;2,4(1H,3H)-Pyrimidinedione, 6-amino-1-methyl-;6-amino-1-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione;EINECS 219-422-3;6-Amino-1-methyl-1H-pyrimidine-2,4-dione;NSC7369;6-Amino-1-methyl-2,4(1H,3H)-pyrimidinedione;SCHEMBL31137;CHEMBL89725;AMY485;SCHEMBL5503560;6-Amino-1-methyluracil, 97%;DTXSID30179076;BCP04504;NSC 7369;NSC-7369;BBL036250;GEO-00177;STL249873;STL509326;AKOS000120920;AKOS025285888;AC-2045;BS-3799;CS-W016441;SB57246;SY049507;BB 0248355;FT-0620904;EN300-19845;H11262;1-Methyl-6-aminopyrimidine-2,4(1H,3H)-dione;6-amino-4-hydroxy-1-methylpyrimidin-2(1H)-one;6-Amino-1-methyl-2,4(1H,3H)-pyrimidinedione #;A852496;W-107329;Q63408603;F1967-1167;Z104475748

Suppliers and Price of 6-Amino-1-methyluracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
6-Amino-1-methyluracil
10g
$ 403.00

TRC
6-Amino-1-methyluracil
50g
$ 195.00

TRC
6-Amino-1-methyluracil
10g
$ 120.00

TCI Chemical
6-Amino-1-methyluracil >98.0%(HPLC)(T)
25g
$ 365.00

TCI Chemical
6-Amino-1-methyluracil >98.0%(HPLC)(T)
5g
$ 98.00

Sigma-Aldrich
6-Amino-1-methyluracil 97%
25g
$ 63.30

Matrix Scientific
6-Amino-1-methyluracil 95%+
2.500g
$ 215.00

Matrix Scientific
6-Amino-1-methyluracil 95%+
1g
$ 101.00

Matrix Scientific
6-Amino-1-methyluracil 95%+
5g
$ 323.00

Crysdot
6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione 97%
1000g
$ 297.00

Total 107 raw suppliers

Chemical Property of 6-Amino-1-methyluracil

Chemical Property:

Appearance/Colour:almost white to slightly beige crystalline powder
Melting Point:300 °C
Refractive Index:1.548
PKA:9.26±0.40(Predicted)
PSA：80.88000
Density:1.339 g/cm³
LogP:-0.76300
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Solubility.:Soluble in diluted sodium hydroxide solution.
XLogP3:-1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:141.053826475
Heavy Atom Count:10
Complexity:221

Purity/Quality:

99%, ^*data from raw suppliers

6-Amino-1-methyluracil ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-36/37/38
Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CN1C(=CC(=O)NC1=O)N
Uses 6-Amino-1-methyluracil is known to exert inhibitory effects towards DNA repair glycosylase. It is also known to be used as a flame retardant. 6-Amino-1-methyluracil may be used in the preparation of 1,1?-di methyl-1H-spiro[pyrimido[4,5-b]quinoline-5,5?-pyrrolo[2,3-d]pyrimidine]-2,2?,4,4?,6?(1?H,3H,3?H,7?H,1?H)-pentaone, via reaction with isatin in the presence of catalytic p-toluene sulfonic acid.

Technology Process of 6-Amino-1-methyluracil

There total 11 articles about 6-Amino-1-methyluracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.2%

: 105-56-6
ethyl 2-cyanoacetate

: 598-50-5
N-Methylurea

: 2434-53-9
6-amino-1-methyluracil

Guidance literature:: N-Methylurea; With sodium ethanolate; In ethanol; at 20 ℃; Reflux;

ethyl 2-cyanoacetate; In ethanol; for 5h; Reagent/catalyst; Solvent;

Reference yield: 87.0%

: 6972-77-6
N-cyanoacetyl-N'-methyl-urea

: 2434-53-9
6-amino-1-methyluracil

Guidance literature:: With chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane; for 24h; Heating;

Reference yield: 70.0%

: 372-09-8
cyanoacetic acid

: 598-50-5
N-Methylurea

: 2434-53-9
6-amino-1-methyluracil

Guidance literature:: cyanoacetic acid; N-Methylurea; With acetic anhydride; at 60 ℃; for 0.166667h; microwave irradiation;

With sodium hydroxide; In ethanol; at 20 ℃;
DOI:10.1016/j.tetlet.2005.06.075