(+/-)-Pindobind

Base Information

Chemical Name:(+/-)-Pindobind
CAS No.:106469-51-6
Molecular Formula:C23H34 Br N3 O3
Molecular Weight:480.445
Hs Code.:
DSSTox Substance ID:DTXSID20910011
Nikkaji Number:J441.683J,J227.593G
ChEMBL ID:CHEMBL157881
Mol file:106469-51-6.mol

Synonyms:N(8)-bromoacetyl-N(1)-3'-(4-indolyloxy)-2'-hydroxypropyl-1,8-diamino-4-menthane;N8-BIM

Suppliers and Price of (+/-)-Pindobind

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(+/-)-PINDOBIND 95.00%
5MG
$ 495.94

Total 22 raw suppliers

Chemical Property of (+/-)-Pindobind

Chemical Property:

Vapor Pressure:2.09E-20mmHg at 25°C
Boiling Point:697.2°Cat760mmHg
PKA:13.84±0.46(Predicted)
Flash Point:375.5°C
PSA：86.38000
Density:1.33g/cm³
LogP:4.51760
Storage Temp.:−20°C
Solubility.:DMSO: soluble
XLogP3:3.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:479.17835
Heavy Atom Count:30
Complexity:566

Purity/Quality:

98%Min ^*data from raw suppliers

(+/-)-PINDOBIND 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CCC(CC1)C(C)(C)NC(=O)CBr)NCC(COC2=CC=CC3=C2C=CN3)O

Technology Process of (+/-)-Pindobind

There total 2 articles about (+/-)-Pindobind which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2380-94-1
1H-indol-4-ol

: 106469-51-6
N⁸-(bromoacetyl)-N¹-<3-(4-indolyloxy)-2-hydroxypropyl>-(Z)-1,8-diamino-p-menthane

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / 1-methylpiperazine / 2 h / Heating

2: 1.) 70 deg C, 5 h, 2.) THF, 25 min

With 1-methyl-piperazine;
DOI:10.1021/jm00387a005