METHYL 4-(4-METHOXYPHENYL)-2,4-DIOXOBUTANOATE

Base Information

• Chemical Name: METHYL 4-(4-METHOXYPHENYL)-2,4-DIOXOBUTANOATE
• CAS No.: 39757-31-8
• Molecular Formula: C12H12O5
• Molecular Weight: 236.224
• Hs Code.: 2918990090
• Mol file: 39757-31-8.mol

Synonyms:(4-Methoxybenzoyl)pyruvicacid methyl ester;Methyl (4-methoxybenzoyl)pyruvate;Methyl (p-methoxybenzoyl)pyruvate;Methyl p-anisoylpyruvate;NSC 208707;

Chemical Property of METHYL 4-(4-METHOXYPHENYL)-2,4-DIOXOBUTANOATE

Chemical Property:

• Vapor Pressure: 1.71E-06mmHg at 25°C
• Melting Point: 96-98
• Refractive Index: 1.513
• Boiling Point: 396.4 °C at 760 mmHg
• Flash Point: 178 °C
• PSA: 72.83000
• Density: 1.21 g/cm³
• LogP: 1.49280

Purity/Quality:

97% ^*data from raw suppliers

Methyl 4-(4-methoxyphenyl)-2,4-dioxobutanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 4-(4-METHOXYPHENYL)-2,4-DIOXOBUTANOATE

There total 2 articles about METHYL 4-(4-METHOXYPHENYL)-2,4-DIOXOBUTANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

Dimethyl oxalate (553-90-2) + 1-(4-methoxyphenyl)ethanone (100-06-1) → methyl (4-methoxybenzoyl)pyruvate (39757-31-8)

Guidance literature:

With sodium methylate; Inert atmosphere;

DOI:10.1016/j.bmcl.2016.02.072

Reference yield:

→ methyl (4-methoxybenzoyl)pyruvate (39757-31-8)

Guidance literature:

p-Methoxyacetophenon, Dimethyloxalat in Gegw. v. NaH;

Reference yield: 94.0%

5-aminotetrazole (4418-61-5) + meta-hydroxybenzaldehyde (100-83-4) + methyl (4-methoxybenzoyl)pyruvate (39757-31-8) → methyl 7-(3-hydroxyphenyl)-6-(4-methoxybenzoyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-5-carboxylate

Guidance literature:

at 120 - 150 ℃;

DOI:10.1134/S1070363220110067

upstream raw materials:

Dimethyl oxalate

1-(4-methoxyphenyl)ethanone

Downstream raw materials:

3-Chloro-4-(4-methoxy-phenyl)-2,4-dioxo-butyric acid methyl ester

4-(4-Methoxy-phenyl)-2,4-dioxo-N-pyridin-2-yl-butyramide

methyl 4-(4-methoxyphenyl)-4-oxo-2-[2-(phenylcarbonyl)hydrazinylidene]butanoate

3-[2-(4-Methoxy-phenyl)-2-oxo-eth-(E)-ylidene]-2-oxo-1,2,3,4-tetrahydro-quinoxaline-6-carbonitrile