2-Cyclopenten-1-one, 3-methyl-2-phenyl-

Base Information

• Chemical Name: 2-Cyclopenten-1-one, 3-methyl-2-phenyl-
• CAS No.: 50397-92-7
• Molecular Formula: C12H12O
• Molecular Weight: 172.227
• Mol file: 50397-92-7.mol

Synonyms:2-Cyclopenten-1-one,3-methyl-2-phenyl;3-methyl-2-phenyl-2-cyclopenten-1-one;2-phenyl-3-methyl-cyclopent-2-ene-1-one;2-phenyl-3-methyl-2-cyclopenten-1-one;3-methyl-2-phenyl-cyclopent-2-enone;2-phenyl-3-methylcyclopent-2-enone;

Chemical Property of 2-Cyclopenten-1-one, 3-methyl-2-phenyl-

Chemical Property:

• PSA: 17.07000
• LogP: 2.82300

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Cyclopenten-1-one, 3-methyl-2-phenyl-

There total 57 articles about 2-Cyclopenten-1-one, 3-methyl-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-methylene-4-phenyl-4-(prop-1-en-2-yl)-1,3-dioxolan-2-one → 3-methyl-2-phenylcyclopent-2-en-1-one (50397-92-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,3,5-trimethyl-benzene; at 110 ℃; for 2h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.1c02401

Reference yield: 94.0%

1-phenyl-hexane-2,5-dione (32776-14-0) → 3-methyl-2-phenylcyclopent-2-en-1-one (50397-92-7)

Guidance literature:

With sodium hydroxide; In ethanol; for 6h; Heating;

DOI:10.1021/jo00246a041

Reference yield: 87.0%

2-bromo-3-methyl-2-cyclopentene-1-one (80963-36-6) + potassium phenyltrifluoborate → 3-methyl-2-phenylcyclopent-2-en-1-one (50397-92-7)

Guidance literature:

With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; toluene; at 90 ℃; for 1.8h;

DOI:10.1021/jo0608366

upstream raw materials:

1-phenyl-hexane-2,5-dione

1-(methoxyphenylmethyl)-2-methylene-1-(trimethylsiloxy)cyclobutane

2-methylfuran

benzyl bromide

Downstream raw materials:

1,3-diphenyl-2-methyl-3-(o-vinylphenyl)cyclopropene

1,4-dihydro-1-methyl-2,3-diphenyl-1,4-methanonaphthalene

1,4-dihydro-3-methyl-1,2-diphenyl-1,4-methanonaphthalene

1-methyl-2,3-diphenyl-1,3-cyclopentadiene