N-[(2-Chloro-6-nitrophenyl)Methyl]glycine Ethyl Ester

Base Information

Chemical Name:N-[(2-Chloro-6-nitrophenyl)Methyl]glycine Ethyl Ester
CAS No.:50608-25-8
Molecular Formula:C11H13ClN2O4
Molecular Weight:272.688
Hs Code.:
Mol file:50608-25-8.mol

Synonyms:N-[(2-Chloro-6-nitrophenyl)methyl]glycine Ethyl Ester;

Suppliers and Price of N-[(2-Chloro-6-nitrophenyl)Methyl]glycine Ethyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[(2-Chloro-6-nitrophenyl)methyl]glycineEthylEster
500mg
$ 1320.00

TRC
N-[(2-Chloro-6-nitrophenyl)methyl]glycineEthylEster
50mg
$ 165.00

Total 4 raw suppliers

Chemical Property of N-[(2-Chloro-6-nitrophenyl)Methyl]glycine Ethyl Ester

Chemical Property:

PSA：84.15000
LogP:2.81500

Purity/Quality:

99% ^*data from raw suppliers

N-[(2-Chloro-6-nitrophenyl)methyl]glycineEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N-[(2-Chloro-6-nitrophenyl)methyl]glycine Ethyl Ester is used as a reactant in the synthesis of oxoquinazoline and dioxobenzothiadiazine hydroxyacetamide derivatives as selective peptide deformylase inhibitors.

Technology Process of N-[(2-Chloro-6-nitrophenyl)Methyl]glycine Ethyl Ester

There total 1 articles about N-[(2-Chloro-6-nitrophenyl)Methyl]glycine Ethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 83-42-1
6-chloro-2-nitrotoluene

: 50608-25-8
N-(2-chloro-6-nitrobenzyl)glycine ethyl ester

Guidance literature:: With N-Bromosuccinimide; Perbenzoic acid; sodium hydrogencarbonate; In ethanol; ethyl acetate; benzene;

Reference yield: 68.0%

: 50608-25-8
N-(2-chloro-6-nitrobenzyl)glycine ethyl ester

: 349150-82-9
N-(2-amino-6-chlorobenzyl)glycine ethyl ester

Guidance literature:: With TEA; hydrogen; nickel; In tetrahydrofuran; at 20 ℃; under 750.075 Torr;
DOI:10.1021/jm000352g

Reference yield:

: 50608-25-8
N-(2-chloro-6-nitrobenzyl)glycine ethyl ester

: 349150-94-3
(1-benzyl-5-chloro-2,2-dioxo-1,4-dihydro-2H-2λ⁶-benzo[1,2,6]thiadiazin-3-yl)-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 68 percent / H₂; TEA / Raney Ni / tetrahydrofuran / 20 °C / 750.08 Torr

2.1: 79 percent / sulfamide; pyridine / 24 h / Heating

3.1: NaH / dimethylformamide / 0.08 h

3.2: 67 percent / Bu₄NI / dimethylformamide / 2 h / 80 °C

With pyridine; TEA; hydrogen; sodium hydride; SULFAMIDE; nickel; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm000352g