1-[2-(4-hydroxyphenyl)ethyl]urea

Base Information

• Chemical Name: 1-[2-(4-hydroxyphenyl)ethyl]urea
• CAS No.: 25017-51-0
• Molecular Formula: C9H12 N2 O2
• Molecular Weight: 180.206
• Mol file: 25017-51-0.mol

Synonyms:Urea,(p-hydroxyphenethyl)- (8CI); Urea, [2-(4-hydroxyphenyl)ethyl]- (9CI)

Chemical Property of 1-[2-(4-hydroxyphenyl)ethyl]urea

Chemical Property:

• Vapor Pressure: 4.04E-06mmHg at 25°C
• Boiling Point: 373.9°Cat760mmHg
• Flash Point: 179.9°C
• Density: 1.227g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-[2-(4-hydroxyphenyl)ethyl]urea

There total 3 articles about 1-[2-(4-hydroxyphenyl)ethyl]urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

tyrosamine (51-67-2) + urea (57-13-6) → N,N'-bis-tyramine urea + (4-hydroxy-phenethyl)-urea (25017-51-0)

Guidance literature:

With iron(II) bromide; In 1,4-dioxane; at 150 ℃; for 6h; Inert atmosphere; Sealed tube;

DOI:10.1002/cssc.201600587

Reference yield:

potassium cyanate (590-28-3) → (4-hydroxy-phenethyl)-urea (25017-51-0)

Guidance literature:

With water; xylene;

Reference yield:

→ (4-hydroxy-phenethyl)-urea (25017-51-0)

Guidance literature:

p-Hydroxy-phenaethyl-amin, KCNO, W.;

DOI:10.1248/yakushi1947.87.1_14

upstream raw materials:

potassium cyanate

tyrosamine

urea

Downstream raw materials:

4,6-diethyl-1-[2-(4-hydroxyphenyl)ethyl]-3a,6a-diphenyl-5-thioxooctahydroimidazo[4,5-d]imidazol-2-one

1,3-dimethylimidazolidine-2,4-dione

6-(2-(4-hydroxyphenyl)ethyl)-2,4-dimethyl-2,4,6,8-tetraazabicyclo[3.3.0]octane-3,7-dione

2,4-imidazolidinedione

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