5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine

Base Information

Chemical Name:5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine
CAS No.:507462-26-2
Molecular Formula:C7H4BrN3O2
Molecular Weight:242.03000
Hs Code.:2933990090
European Community (EC) Number:803-833-5
DSSTox Substance ID:DTXSID20694581
Wikidata:Q82623735
Mol file:507462-26-2.mol

Synonyms:5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine;507462-26-2;1H-Pyrrolo[2,3-b]pyridine, 5-bromo-3-nitro-;SCHEMBL7114099;DTXSID20694581;GHHWPSOGKLMSCJ-UHFFFAOYSA-N;AMY24644;CS-B0571;MFCD12405111;AKOS022172414;DS-5980;SB14401;FT-0701561;1H-Pyrrolo[2,3-b]pyridine,5-bromo-3-nitro-;EN300-212152;P16114;5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine, AldrichCPR

Suppliers and Price of 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine
100mg
$ 75.00

Sigma-Aldrich
5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine Aldrich
1g
$ 201.00

Matrix Scientific
5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine 95%
25g
$ 4410.00

Matrix Scientific
5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine 95%
5g
$ 1143.00

Matrix Scientific
5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine 95%
1g
$ 269.00

Chemenu
5-bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine 95%+
25g
$ 519.00

Chemenu
5-bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine 95%+
1g
$ 70.00

Chemenu
5-bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine 95%+
5g
$ 187.00

Ambeed
5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine 97%
5g
$ 94.00

Alichem
5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine
5g
$ 787.50

Total 27 raw suppliers

Chemical Property of 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine

Chemical Property:

PSA：74.50000
LogP:2.75680
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:240.94869
Heavy Atom Count:13
Complexity:220

Purity/Quality:

99%, ^*data from raw suppliers

5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:

Useful:

Canonical SMILES:C1=C(C=NC2=C1C(=CN2)[N+](=O)[O-])Br

Technology Process of 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine

There total 3 articles about 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 183208-35-7
5-bromo-1H-pyrrolo[2,3-b]pyridine

: 507462-26-2
5-bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: With nitric acid; at 0 ℃; for 0.666667h;
DOI:10.1021/acs.jmedchem.9b00136

Reference yield:

: 381233-96-1
2-amino-3-iodo-5-bromopyridine

: 507462-26-2
5-bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

2: potassium tert-butylate / 1-methyl-pyrrolidin-2-one / 1 h / 80 °C

3: nitric acid / 0.67 h / 0 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium tert-butylate; nitric acid; triethylamine; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; 1: |Sonogashira Cross-Coupling;
DOI:10.1021/acs.jmedchem.9b00136

Reference yield:

: 905966-34-9
5-bromo-3-(2-(trimethylsilyl)ethynyl)pyridine-2-amine

: 507462-26-2
5-bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / 1-methyl-pyrrolidin-2-one / 1 h / 80 °C

2: nitric acid / 0.67 h / 0 °C

With potassium tert-butylate; nitric acid; In 1-methyl-pyrrolidin-2-one;
DOI:10.1021/acs.jmedchem.9b00136