7-Ampcc

Base Information

• Chemical Name: 7-Ampcc
• CAS No.: 112601-22-6
• Molecular Formula: C₂₁H₁₉N₇O₅S₂
• Molecular Weight: 513.558
• Mol file: 112601-22-6.mol

Synonyms:7-(2-(2-aminothiazolyl)-2-methoxyiminoacetamido)-3-(imidazo(1,2-a)pyridinium-1-yl)methyl-3-cephem-4-carboxylate;7-AMPCC

Chemical Property of 7-Ampcc

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 216.83000
• Density: g/cm³
• LogP: -0.57160
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 6
• Exact Mass: 513.08890908
• Heavy Atom Count: 35
• Complexity: 957

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=C5C=CC=CN5C=C4)C(=O)[O-]
• Isomeric SMILES: CO/N=C(\C1=CSC(=N1)N)/C(=O)N[C@@H]2[C@H]3N(C2=O)C(=C(CS3)C[N+]4=C5C=CC=CN5C=C4)C(=O)[O-]

Technology Process of 7-Ampcc

There total 5 articles about 7-Ampcc which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

imidazo[1,2-a]pyridine (274-76-0) + 7β-[2-(2-aminothiazol-4-yl)-2-(Z)-methoxyiminoacetamido]-3-hydroxymethyl-3-cephem-4-carboxylic acid (152186-44-2,121020-94-8,74440-61-2,99124-78-4) → 7β-[2-(2-aminothiazol-4-yl)-2-(Z)-methoxyiminoacetamido]-3-(imidazo[1,2-a]pyridinium-1-yl)-methyl-3-cephem-4-carboxylate (112601-22-6)

Guidance literature:

With acetic acid; triethyl phosphite; In tetrahydrofuran; water; formamide; acetonitrile;

Reference yield:

imidazo[1,2-a]pyridine (274-76-0) + 7β-[2-(2-aminothiazol-4-yl)-2(Z)-methoxyiminoacetamido]-3-(3-oxobutyryloxymethyl)-3-cephem-4-carboxylic acid → 7β-[2-(2-aminothiazol-4-yl)-2(Z)-methoxyiminoacetamido]-3-[(imidazo[1,2-a]pyridinium-1-yl)methyl]-3-cephem-4-carboxylate (112601-22-6)

Guidance literature:

With potassium iodide; In water; acetonitrile;

Reference yield:

imidazo[1,2-a]pyridine (274-76-0) + 7β-[2-(2-aminothiazol-4-yl)-(Z)-2-methoxyiminoacetoamido]-3-acetoxymethyl-3-cephem-4-carboxylic acid (152186-43-1) → 7β-[2-(2-aminothiazol-4-yl)-2(Z)-methoxyiminoacetamido]-3-[(imidazo[1,2-a]pyridinium-1-yl)methyl]-3-cephem-4-carboxylate (112601-22-6)

Guidance literature:

With potassium iodide; In water; ethyl acetate; acetonitrile;

upstream raw materials:

imidazo[1,2-a]pyridine

7β-[2-(2-aminothiazol-4-yl)-2-(Z)-methoxyiminoacetamido]-3-hydroxymethyl-3-cephem-4-carboxylic acid

7β-((Z)-(2-amino-1,3-thiazol-4-yl)-2-methoximinoacetamido)-3-hydroxymethyl-3-cephem-4-carboxylic acid

ethanol