Pyridine, 3-((1R,2S)-1-methyl-1-oxido-2-pyrrolidinyl)-

Base Information Edit

Chemical Name:Pyridine, 3-((1R,2S)-1-methyl-1-oxido-2-pyrrolidinyl)-
CAS No.:51020-67-8
Molecular Formula:C10H14N2O
Molecular Weight:178.234
Hs Code.:
UNII:PDW66UMA66
Nikkaji Number:J527.038C
Wikidata:Q27286495
Mol file:51020-67-8.mol

Synonyms:(1R,2S)-Anti-nicotine N'-oxide;UNII-PDW66UMA66;51020-67-8;PDW66UMA66;Nicotine N'-oxide, (1'R,2'S)-;Pyridine, 3-((1R,2S)-1-methyl-1-oxido-2-pyrrolidinyl)-;(1'R,2'S)-cis-Nicotine-1'-N-oxide;1'(R),2'(S)-cis-Nicotine-N'-oxide;1'(R),2'(S)-cis-Nicotine-N'-oxide, (-)-;3-(1-Methyl-2-pyrrolidinyl)-pyridine, N-oxide, (1R-trans)-;3-[(1R,2S)-1-methyl-1-oxidopyrrolidin-1-ium-2-yl]pyridine;cis-NOX;cis-nicotine n'-oxide;cis-(S)-nicotine N(1')-oxide;(1'R,2'S)-nicotine N'-oxide;CHEBI:142661;AKOS040762119;Nicotine N/'-oxide, (1/'R,2/'S)-;Q27286495;3-[(1R,2S)-1-methyl-1-oxidopyrrolidin-2-yl]pyridine

Suppliers and Price of Pyridine, 3-((1R,2S)-1-methyl-1-oxido-2-pyrrolidinyl)-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Pyridine, 3-((1R,2S)-1-methyl-1-oxido-2-pyrrolidinyl)- Edit

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:178.110613074
Heavy Atom Count:13
Complexity:186

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[N+]1(CCCC1C2=CN=CC=C2)[O-]
Isomeric SMILES:C[N@+]1(CCC[C@H]1C2=CN=CC=C2)[O-]

Technology Process of Pyridine, 3-((1R,2S)-1-methyl-1-oxido-2-pyrrolidinyl)-

There total 7 articles about Pyridine, 3-((1R,2S)-1-methyl-1-oxido-2-pyrrolidinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 54-11-5
nicotin

: 29419-54-3,29419-55-4,51020-67-8,51095-86-4,491-26-9,63551-14-4
nicotine-1'-N-oxide

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; at 0 ℃; for 1.5h; Inert atmosphere;
DOI:10.1002/jhet.841

Reference yield: 27.5%

: 54-11-5
nicotin

: 494-97-3,13450-58-3
nornicotine

: 5980-06-3,17114-40-8
S-(-)-Norcotinine

: 486-56-6
cotinine

: 491-26-9,29419-54-3,29419-55-4,51020-67-8,51095-86-4,63551-14-4
Nicotine-N-oxide

Guidance literature:: With air; cofactor solution; phenobarbitone-induced rabbit hepatic homogenate; In phosphate buffer; at 37 ℃; for 1h; pH=7.4; Further byproducts given;
DOI:10.1002/(SICI)1099-1344(199904)42:4<387::AID-JLCR203>3.0.CO;2-5