3-(1-Methylpyrrolidin-2-yl)pyridine

Base Information

Chemical Name:3-(1-Methylpyrrolidin-2-yl)pyridine
CAS No.:22083-74-5
Molecular Formula:C10H14 N2
Molecular Weight:162.235
Hs Code.:
European Community (EC) Number:623-834-2
NSC Number:5065
UN Number:1654
DSSTox Substance ID:DTXSID3048154
Nikkaji Number:J23.948H
Wikidata:Q12144
Pharos Ligand ID:U94HYPVTTQUG
Metabolomics Workbench ID:134051
ChEMBL ID:CHEMBL440464
Mol file:22083-74-5.mol

Synonyms:22083-74-5;3-(1-methylpyrrolidin-2-yl)pyridine;(+/-)-Nicotine;(R,S)-Nicotine;Pyridine, 3-(1-methyl-2-pyrrolidinyl)-;(+-)-Nicotine;Nikotin;DL-Nicotine;(RS)-Nicotine;Nicotine, (+-)-;[3H]NICOTINE;(+/-)-Nicotine-d7;75202-10-7;3-(1-Methyl-2-pyrrolidinyl)pyridine;CHEMBL440464;(+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine;NSC5065;1-Methyl-2-(3-pyridyl)pyrrolidine;3-[1-Methylpyrrolidin-2-yl]pyridine;BRN 0082111;destruxol;1-Methyl-2-(3-pyridyl]pyrrolidine;S-(-)-Nicotine;DL-tetrahydronicotyrine;1219805-86-3;SMR000471862;methyl-2-pyrrolidinyl)pyridine;CHEBI:18723;rac-Nicotine;racemic nicotine;1-methyl-2-(3-pyridal)-pyrrolidene;Flux Maay;Nicotine, liquid;niagara p.a.;Nicotine-(+);Ortho N-4;Ortho N-5;Nicotine (not validated);D02BPT;(+/-)NICOTINE;SCHEMBL20193;MLS001066400;MLS001332491;GTPL3978;XL All Insecti-cide, Emo-Nib;DTXSID3048154;SCHEMBL11976729;CHEBI:138000;US8609708, 54 Nicotine;GLXC-19133;HMS2267D10;HMS3373A19;WLN: T6NJ C- BT5NTJ A1;BBL028104;BDBM50004108;STL146319;1-methyl-2-(3-pyridyl) pyrrolidine;AKOS005720800;AB05474;VS-0124;NCGC00161830-01;BP-13421;LS-96489;.beta.-Pyridyl-.alpha.-N-methylpyrrolidine;(+/-)-Nicotine, >=99% (TLC), liquid;(+/-)-3-(1-Methyl-2-pyrrolidinyl)pyridine;3-(tetrahydro-1-methyl pyrrol-2-yl)Pyridine;EN300-123020;Q12144;AB00919090_06;J-014481;3-(1-METHYL-4,5-DIHYDRO-3H-PYRROL-5-YL)PYRIDINE

Suppliers and Price of 3-(1-Methylpyrrolidin-2-yl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
rac-Nicotine
2g
$ 1120.00

TRC
rac-Nicotine
500mg
$ 320.00

Sigma-Aldrich
(±)-Nicotine ≥99% (TLC), liquid
1g
$ 610.00

Sigma-Aldrich
(±)-Nicotine ≥99% (TLC), liquid
500mg
$ 332.00

Sigma-Aldrich
(±)-Nicotine ≥99% (TLC), liquid
100mg
$ 96.80

Medical Isotopes, Inc.
(+/-)-Nicotine
250 mg
$ 840.00

Cayman Chemical
(±)-Nicotine ≥98%
100mg
$ 82.00

Cayman Chemical
(±)-Nicotine ≥98%
500mg
$ 267.00

Cayman Chemical
(±)-Nicotine ≥98%
250mg
$ 144.00

AK Scientific
(+/-)-Nicotine
500mg
$ 488.00

Total 75 raw suppliers

Chemical Property of 3-(1-Methylpyrrolidin-2-yl)pyridine

Chemical Property:

Vapor Pressure:0.0303mmHg at 25°C
Melting Point:-79 °C
Boiling Point:244.4°Cat760mmHg
PKA:8.02(at 25℃)
Flash Point:101.7°C
PSA：16.13000
Density:1.032g/cm³
LogP:1.78620
Storage Temp.:Refrigerator
Solubility.:ethanol: 50 mg/mL
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:162.115698455
Heavy Atom Count:12
Complexity:147
Transport DOT Label:Poison

Purity/Quality:

≥98% ^*data from raw suppliers

rac-Nicotine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T+,N
Statements: 25-27-51/53
Safety Statements: 36/37-45-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CN1CCCC1C2=CN=CC=C2
Recent EU Clinical Trials:A double-blind, randomized, placebo- and NRT-controlled Phase II study to assess the effects of EVT 302 alone and in combination with NRT on craving and withdrawal in healthy male smokers deprived of cigarettes
Uses This is the unnatural isomer of Nicotine (+/-)-NICOTINE is an alkaloid isolated from plants. It is an active stimulant, having both addictive and carcinogenic properties. Nicotine is an alkaloid isolated from plants. Nicotine is an active stimulant, having both addictive and carcinogenic properties. Nicotine can be absorbed through the alimentary canal, respiratory tra ct and intact skin. Nicotine is used in the treatment of smoking withdrawal syndrome. Nicotine has been used as an anthelmintic.

Technology Process of 3-(1-Methylpyrrolidin-2-yl)pyridine

There total 88 articles about 3-(1-Methylpyrrolidin-2-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.1%