5-Chloroquinoline-2-carboxylic acid

Base Information

Chemical Name:5-Chloroquinoline-2-carboxylic acid
CAS No.:511231-70-2
Molecular Formula:C10H6ClNO2
Molecular Weight:207.61300
Hs Code.:2933499090
Mol file:511231-70-2.mol

Synonyms:2-Quinolinecarboxylic acid,5-chloro;5-Chlor-chinolin-2-carbonsaeure;5-chloro-quinoline-2-carboxylic acid;

Suppliers and Price of 5-Chloroquinoline-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Chloroquinoline-2-carboxylicacid 98%
1g
$ 475.00

Chemenu
5-chloroquinoline-2-carboxylicacid 98%
1g
$ 449.00

Ambeed
5-Chloroquinoline-2-carboxylicacid 98%
250mg
$ 222.00

Ambeed
5-Chloroquinoline-2-carboxylicacid 98%
100mg
$ 139.00

Ambeed
5-Chloroquinoline-2-carboxylicacid 98%
1g
$ 593.00

Alichem
5-Chloroquinoline-2-carboxylicacid
1g
$ 772.74

Abosyn
5-Chloroquinoline-2-carboxylicacid 95-98%
1g
$ 612.00

Total 15 raw suppliers

Chemical Property of 5-Chloroquinoline-2-carboxylic acid

Chemical Property:

Melting Point:176 °C (decomp)
Boiling Point:382.1±27.0 °C(Predicted)
PKA:4.16±0.50(Predicted)
PSA：50.19000
Density:1.469±0.06 g/cm3(Predicted)
LogP:2.58640
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

5-Chloroquinoline-2-carboxylicacid 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Chloroquinoline-2-carboxylic acid

There total 6 articles about 5-Chloroquinoline-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35490-90-5
2-amino-6-chlorobenzaldehyde

: 57-60-3
piruvate

: 511231-70-2
5-chloro-quinoline-2-carboxylic acid

Guidance literature:: With Pseudomonas putida trans-o-hydroxybenzylidenepyruvate hydratase-aldolase; In aq. phosphate buffer; dimethyl sulfoxide; at 20 ℃; for 16h; pH=6.5; Enzymatic reaction;
DOI:10.1021/acscatal.1c01398

Reference yield:

: 6361-22-4
2-chloro-6-nitrobenzaldehyde

: 511231-70-2
5-chloro-quinoline-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: iron; hydrogenchloride / ethanol; water / 1 h / 80 °C

2: Pseudomonas putida trans-o-hydroxybenzylidenepyruvate hydratase-aldolase / dimethyl sulfoxide; aq. phosphate buffer / 16 h / 20 °C / pH 6.5 / Enzymatic reaction

With hydrogenchloride; Pseudomonas putida trans-o-hydroxybenzylidenepyruvate hydratase-aldolase; iron; In aq. phosphate buffer; ethanol; water; dimethyl sulfoxide;
DOI:10.1021/acscatal.1c01398