O-[4-Hydroxy-3-(propan-2-yl)phenyl]-3,5-diiodo-L-tyrosine

Base Information

Chemical Name:O-[4-Hydroxy-3-(propan-2-yl)phenyl]-3,5-diiodo-L-tyrosine
CAS No.:51-23-0
Molecular Formula:C₁₈H₁₉I₂NO₄
Molecular Weight:567.162
Hs Code.:
ChEMBL ID:CHEMBL3275207
DSSTox Substance ID:DTXSID30552961
Nikkaji Number:J646.290A
Wikidata:Q82433406
Mol file:51-23-0.mol

Synonyms:51-23-0;SCHEMBL5545767;CHEMBL3275207;DTXSID30552961;O-[4-Hydroxy-3-(propan-2-yl)phenyl]-3,5-diiodo-L-tyrosine;3'-isopropyl-3,5-diiodo-l-thyronine

Suppliers and Price of O-[4-Hydroxy-3-(propan-2-yl)phenyl]-3,5-diiodo-L-tyrosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of O-[4-Hydroxy-3-(propan-2-yl)phenyl]-3,5-diiodo-L-tyrosine

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:566.94035
Heavy Atom Count:25
Complexity:439

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=C(C=CC(=C1)OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)O
Isomeric SMILES:CC(C)C1=C(C=CC(=C1)OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)O

Technology Process of O-[4-Hydroxy-3-(propan-2-yl)phenyl]-3,5-diiodo-L-tyrosine

There total 5 articles about O-[4-Hydroxy-3-(propan-2-yl)phenyl]-3,5-diiodo-L-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 23241-32-9
L-N-Acetyl-3-<3,5-diiod-4-(4-methoxy-3-isopropyl-phenoxy)-phenyl>-2-amino-propionsaeure-ethylester

: 51-23-0
L-3,5-Diiod-3'-isopropyl-thyronin

Guidance literature:: With hydrogen iodide; acetic acid;
DOI:10.1021/jm00341a020

Reference yield:

: 13523-62-1
3-iso-propyl-4-methoxyphenol

: 51-23-0
L-3,5-Diiod-3'-isopropyl-thyronin

Guidance literature:: Multi-step reaction with 3 steps

1: (i) TsCl, Py, (ii) /BRN= 1938872/

2: (i) H₂, Pd-C, AcOH, (ii) NaNO₂, H₂SO₄, (iii) I₂, NaI, urea

3: aq. HI, AcOH

With hydrogen iodide; acetic acid;
DOI:10.1021/jm00341a020

Reference yield:

: 100769-25-3
L-N-Acetyl-3-<3,5-dinitro-4-(4-methoxy-3-isopropyl-phenoxy)-phenyl>-2-amino-propionsaeure-ethylester

: 51-23-0
L-3,5-Diiod-3'-isopropyl-thyronin

Guidance literature:: Multi-step reaction with 2 steps

1: (i) H₂, Pd-C, AcOH, (ii) NaNO₂, H₂SO₄, (iii) I₂, NaI, urea

2: aq. HI, AcOH

With hydrogen iodide; acetic acid;
DOI:10.1021/jm00341a020