Butanoic acid, 4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-4-[[[3-(trifluoromethyl)phenyl] methyl]amino]-, 1,1-dimethylethyl ester, (3R)-

Base Information

Chemical Name:Butanoic acid, 4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-4-[[[3-(trifluoromethyl)phenyl] methyl]amino]-, 1,1-dimethylethyl ester, (3R)-
CAS No.:512783-84-5
Molecular Formula:C24H27F3N2O5
Molecular Weight:480.484
Hs Code.:
Mol file:512783-84-5.mol

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Butanoic acid, 4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-4-[[[3-(trifluoromethyl)phenyl] methyl]amino]-, 1,1-dimethylethyl ester, (3R)-

Chemical Property:

Purity/Quality:

Safty Information:

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Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Butanoic acid, 4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-4-[[[3-(trifluoromethyl)phenyl] methyl]amino]-, 1,1-dimethylethyl ester, (3R)-

There total 1 articles about Butanoic acid, 4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-4-[[[3-(trifluoromethyl)phenyl] methyl]amino]-, 1,1-dimethylethyl ester, (3R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 2740-83-2
3-(TRIFLUOROMETHYL)BENZYLAMINE

: 71449-08-6
(2R)-2-{[(benzyloxy)carbonyl]amino}-4-tert-butoxy-4-oxobutanoic acid

: 512783-84-5
N-[(benzyloxy)carbonyl]-D-aspartic acid β-tert-butyl ester α-[3-(trifluoromethyl)benzyl]amide

Guidance literature:: With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmc.2006.12.031

Reference yield: 96.0%

: 512783-84-5
N-[(benzyloxy)carbonyl]-D-aspartic acid β-tert-butyl ester α-[3-(trifluoromethyl)benzyl]amide

: 512783-90-3
D-aspartic acid β-tert-butyl ester α-[3-(trifluoromethyl)benzyl]amide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1016/j.bmc.2006.12.031

Reference yield:

: 512783-84-5
N-[(benzyloxy)carbonyl]-D-aspartic acid β-tert-butyl ester α-[3-(trifluoromethyl)benzyl]amide

: 3-(3-phenyl-allylideneamino)-N-(3-trifluoromethyl-benzyl)-succinamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / hydrogen / palladium on carbon / methanol

2: magnesium sulfate / CH₂Cl₂ / 20 °C

With hydrogen; magnesium sulfate; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1016/j.bmc.2006.12.031