4-Amino-2-[(pyrrolidin-1-yl)methyl]phenol

Base Information

Chemical Name:4-Amino-2-[(pyrrolidin-1-yl)methyl]phenol
CAS No.:51387-91-8
Molecular Formula:C₁₁H₁₆N₂O
Molecular Weight:192.261
Hs Code.:
ChEMBL ID:CHEMBL4302592
DSSTox Substance ID:DTXSID40547121
Wikidata:Q82425148
Mol file:51387-91-8.mol

Synonyms:51387-91-8;CHEMBL4302592;DTXSID40547121;4-Amino-2-[(pyrrolidin-1-yl)methyl]phenol

Suppliers and Price of 4-Amino-2-[(pyrrolidin-1-yl)methyl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 4-Amino-2-[(pyrrolidin-1-yl)methyl]phenol

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:192.126263138
Heavy Atom Count:14
Complexity:180

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)CC2=C(C=CC(=C2)N)O

Technology Process of 4-Amino-2-[(pyrrolidin-1-yl)methyl]phenol

There total 5 articles about 4-Amino-2-[(pyrrolidin-1-yl)methyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13886-02-7
N-(4-Hydroxy-3-pyrrolidinomethylphenyl)acetamid

: 51387-91-8
2-(1-pyrrolidinylmethyl)-4-aminophenol

Guidance literature:: With hydrogenchloride; for 3h; Heating;
DOI:10.1211/0022357011777765

Reference yield:

: 147197-22-6
4-nitro-2-(pyrrolidin-1'-ylmethyl)phenol

: 51387-91-8
2-(1-pyrrolidinylmethyl)-4-aminophenol

Guidance literature:: With ammonia; hydrogen; nickel; In ethanol;

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 51387-91-8
2-(1-pyrrolidinylmethyl)-4-aminophenol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.55 g / ethanol / 2 h / 100 °C

2: H₂, NH₃ / Raney Ni / ethanol

With ammonia; hydrogen; nickel; In ethanol;