2-Thienylglyoxal

Base Information

• Chemical Name: 2-Thienylglyoxal
• CAS No.: 51445-63-7
• Molecular Formula: C6H4O2S
• Molecular Weight: 140.163
• Hs Code.: 2934999090
• Mol file: 51445-63-7.mol

Synonyms:2-oxo-2-(2-thienyl)acetaldehyde;(2-thienyl)methyl isocyanate;thiophen-2-ylglyoxal;2-thienyl-glyoxal;2-thiopheneglyoxal;2-thenyl isocyanate;(thien-2-yl)methyl isocyanate;thiophene-2-glyoxal;thiophen-2-ylmethyl isocyanate;thiophen-2-yl-oxoacetaldehyde;

Chemical Property of 2-Thienylglyoxal

Chemical Property:

• Vapor Pressure: 0.192mmHg at 25°C
• Melting Point: 87 °C
• Boiling Point: 210.5oC at 760 mmHg
• Flash Point: 81.1oC
• PSA: 71.61000
• Density: 1.3g/cm3
• LogP: 1.06540

Purity/Quality:

98%Min ^*data from raw suppliers

2-Thienylglyoxal hydrate 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Thienylglyoxal

There total 9 articles about 2-Thienylglyoxal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-Acetylthiophene (88-15-3,97511-16-5) → oxo-thiophen-2-yl-acetaldehyde (51445-63-7)

Guidance literature:

With selenium (IV) oxide; In 1,4-dioxane; water; Heating;

DOI:10.1016/j.bmcl.2008.02.037

Reference yield:

2-thienyl lithium (2786-07-4) + carbon monoxide (201230-82-2) → oxo-thiophen-2-yl-acetaldehyde (51445-63-7) + 2,2'-Bithiophene (492-97-7) + 2,5-dihydro-2-thiophenecarboxaldehide

Guidance literature:

In tetrahydrofuran; at 0 ℃; under 759.811 Torr; Further Variations:; Solvents; Product distribution;

DOI:10.1002/poc.661

Reference yield:

2-iodo-1-(thiophen-2-yl)ethanone (55984-19-5) → oxo-thiophen-2-yl-acetaldehyde (51445-63-7)

Guidance literature:

With iodine; potassium hydroxide; In water; dimethyl sulfoxide; at 100 ℃;

DOI:10.1021/jo302754c

upstream raw materials:

2-Acetylthiophene

(E)-2-(furan-2-yl)-2-oxoacetaldehyde oxime

2-thienyl lithium

carbon monoxide

Downstream raw materials:

2-(thiophen-2-yl)quinoxaline

Schiff base derived from bis-p(aminophenyl) sulphide and 2-acetyl thiophene glyoxal

Cyano-acetic acid 1-cyclohexylcarbamoyl-2-oxo-2-thiophen-2-yl-ethyl ester

2-thienylglyoxal-4'-chloro-1-iminobenzene

Refernces

• 1、 Kuzu, Burak,Ekmekci, Zeynep,Tan, Meltem,Menges, Nurettin. "Excited State Intramolecular Proton Transfer (ESIPT)-Based Sensor for Ion Detection". . p. 861 - 872. Retrieved 2021/04/05.
• 2、 Luo, Xiaosheng,Wang, Ping. "Ynonylation of Acyl Radicals by Electroinduced Homolysis of 4-Acyl-1,4-dihydropyridines". supporting information. p. 4960 - 4965. Retrieved 2021/07/20.