1-Allyl-2-(benzyloxy)benzene

Base Information

• Chemical Name: 1-Allyl-2-(benzyloxy)benzene
• CAS No.: 51496-94-7
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• DSSTox Substance ID: DTXSID10466916
• Nikkaji Number: J2.868.743E
• Wikidata: Q82293583
• Mol file: 51496-94-7.mol

Synonyms:1-allyl-2-(benzyloxy)benzene;51496-94-7;1-Phenylmethoxy-2-prop-2-enylbenzene;Benzene, 1-(phenylmethoxy)-2-(2-propenyl)-;2-allylphenyl benzyl ether;1-Allyl-2-benzyloxybenzene;SCHEMBL7805002;DTXSID10466916;KOINYZYCRQIVGM-UHFFFAOYSA-N;FT-0753027;A1-05159

Chemical Property of 1-Allyl-2-(benzyloxy)benzene

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 224.120115130
• Heavy Atom Count: 17
• Complexity: 218

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCC1=CC=CC=C1OCC2=CC=CC=C2

Technology Process of 1-Allyl-2-(benzyloxy)benzene

There total 3 articles about 1-Allyl-2-(benzyloxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

benzyl chloride (100-44-7) + o-Allylphenol (1745-81-9) → 1-allyl-2-(benzyloxy)benzene (51496-94-7)

Guidance literature:

With potassium carbonate; In acetonitrile; at 80 ℃; for 18h;

Reference yield: 96.0%

benzyl bromide (100-39-0) + o-Allylphenol (1745-81-9) → 1-allyl-2-(benzyloxy)benzene (51496-94-7)

Guidance literature:

With potassium carbonate; In acetone; for 4h; Inert atmosphere; Reflux;

DOI:10.1055/s-0028-1088077

Reference yield: 88.0%

methyl-triphenylphosphonium iodide (2065-66-9) + 2-(2-(benzyloxy)phenyl)acetaldehyde (179253-16-8) → 1-allyl-2-(benzyloxy)benzene (51496-94-7)

Guidance literature:

methyl-triphenylphosphonium iodide; With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

2-(2-(benzyloxy)phenyl)acetaldehyde; In tetrahydrofuran; at 20 ℃; for 2h; Further stages.;

DOI:10.1016/j.tet.2008.03.001

upstream raw materials:

benzyl bromide

o-Allylphenol

methyl-triphenylphosphonium iodide

2-(2-(benzyloxy)phenyl)acetaldehyde

Downstream raw materials:

(2,3-dihydro-2-benzofuranyl)-methyl bromide

2-(2-(benzyloxy)phenyl)acetaldehyde

(E)-1-benzyloxy-2-(prop-1-enyl)benzene

3-(2-benzyloxy-phenyl)-propan-1-ol