3-Hydroxy-3-phenyl-2-(prop-2-en-1-yl)-2,3-dihydro-1h-isoindol-1-one

Base Information

Chemical Name:3-Hydroxy-3-phenyl-2-(prop-2-en-1-yl)-2,3-dihydro-1h-isoindol-1-one
CAS No.:3532-75-0
Molecular Formula:C₁₇H₁₅NO₂
Molecular Weight:265.312
Hs Code.:
NSC Number:67326
DSSTox Substance ID:DTXSID80290205
Mol file:3532-75-0.mol

Synonyms:2-Allyl-3-hydroxy-3-phenylisoindolin-1-one;3532-75-0;3-hydroxy-3-phenyl-2-(prop-2-en-1-yl)-2,3-dihydro-1h-isoindol-1-one;NSC67326;DTXSID80290205;NSC-67326;AKOS023556229

Suppliers and Price of 3-Hydroxy-3-phenyl-2-(prop-2-en-1-yl)-2,3-dihydro-1h-isoindol-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 3-Hydroxy-3-phenyl-2-(prop-2-en-1-yl)-2,3-dihydro-1h-isoindol-1-one

Chemical Property:

Vapor Pressure:2.06E-09mmHg at 25°C
Boiling Point:464.1°Cat760mmHg
Flash Point:234.5°C
Density:1.234g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:265.110278721
Heavy Atom Count:20
Complexity:389

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=CCN1C(=O)C2=CC=CC=C2C1(C3=CC=CC=C3)O

Technology Process of 3-Hydroxy-3-phenyl-2-(prop-2-en-1-yl)-2,3-dihydro-1h-isoindol-1-one

There total 6 articles about 3-Hydroxy-3-phenyl-2-(prop-2-en-1-yl)-2,3-dihydro-1h-isoindol-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 2051-90-3
Dichlorodiphenylmethane

: 1476-23-9
allylisocyanate

: 128425-78-5,3532-75-0
2-allyl-3-hydroxy-3-phenyl-2,3-dihydro-isoindol-1-one

Guidance literature:: Dichlorodiphenylmethane; allylisocyanate; With antimonypentachloride; In dichloromethane; at -40 - 23 ℃;

With sodium hydroxide; In dichloromethane; water; at 0 ℃; for 0.333333h;

Reference yield:

: 85-52-9
2-Benzoylbenzoic acid

: 128425-78-5,3532-75-0
2-allyl-3-hydroxy-3-phenyl-2,3-dihydro-isoindol-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 1) RT, 3 h, 2) reflux, 15 min

2: triethylamine / CHCl₃ / Ambient temperature; overnight

With thionyl chloride; triethylamine; In chloroform;

Reference yield:

: 136918-14-4,85-41-6
phthalimide

: 128425-78-5,3532-75-0
2-allyl-3-hydroxy-3-phenyl-2,3-dihydro-isoindol-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 17 h

2: 1) Mg / 1) ether, 2) THF, 0 deg C, 5h

With magnesium; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran;