1-naphthalen-2-yl-3-phenyl-urea

Base Information

• Chemical Name: 1-naphthalen-2-yl-3-phenyl-urea
• CAS No.: 6299-42-9
• Molecular Formula: C17H14 N2 O
• Molecular Weight: 262.311
• Hs Code.: 2924299090
• Mol file: 6299-42-9.mol

Synonyms:Urea,1-(2-naphthyl)-3-phenyl- (6CI,7CI,8CI); NSC 44661

Chemical Property of 1-naphthalen-2-yl-3-phenyl-urea

Chemical Property:

• Vapor Pressure: 2.34E-05mmHg at 25°C
• Boiling Point: 359.6°C at 760 mmHg
• Flash Point: 126.1°C
• PSA: 41.13000
• Density: 1.286g/cm³
• LogP: 4.62980

Purity/Quality:

99%min ^*data from raw suppliers

N-2-NAPHTHYL-N'-PHENYLUREA 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-naphthalen-2-yl-3-phenyl-urea

There total 11 articles about 1-naphthalen-2-yl-3-phenyl-urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

aniline (62-53-3) + (1H-benzo[d][1,2,3]triazol-1-yl)(naphthalen-2-yl)methanone (177960-06-4) → NSC 44661 (6299-42-9)

Guidance literature:

With trimethylsilylazide; triethylamine; In toluene; at 110 ℃; for 1h; Sealed tube;

DOI:10.1055/s-0039-1689937

Reference yield: 91.0%

3-(naphthalen-2-yl)-1,4,2-dioxazol-5-one + aniline (62-53-3) → NSC 44661 (6299-42-9)

Guidance literature:

With sodium acetate; In methanol; at 60 ℃; for 2h;

Reference yield: 67.0%

aniline (62-53-3) + naphthalene-2-carboxylate (93-09-4) → NSC 44661 (6299-42-9)

Guidance literature:

With diphenyl phosphoryl azide; triethylamine; In toluene; at 100 ℃; for 0.0166667h; Microwave irradiation;

DOI:10.1021/acs.joc.6b02521

upstream raw materials:

1-naphthalen-2-yl-3-phenyl-thiourea

phenyl isocyanate

naphthalen-2-ylamine

2-naphthoyl azide

Refernces

• 1、 -. "Synthetic method and application of urea compound". Paragraph 0118-0121. . Retrieved 2019/06/07.
• 2、 Kulkarni, Abhijit R.,Garai, Sumanta,Thakur, Ganesh A.. "Scalable, One-Pot, Microwave-Accelerated Tandem Synthesis of Unsymmetrical Urea Derivatives". . p. 992 - 999. Retrieved 2018/06/18.