(2-Amino-5-benzoylphenyl)acetic acid

Base Information

Chemical Name:(2-Amino-5-benzoylphenyl)acetic acid
CAS No.:51579-81-8
Molecular Formula:C15H13NO3
Molecular Weight:255.273
Hs Code.:
ChEMBL ID:CHEMBL28972
DSSTox Substance ID:DTXSID10539831
Wikidata:Q82415639

Synonyms:(2-Amino-5-benzoylphenyl)acetic acid;51579-81-8;CHEMBL28972;SCHEMBL10696478;DTXSID10539831;XEUUQQCQFHDEBD-UHFFFAOYSA-N;2-Amino-5-benzoylphenylacetic Acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2-Amino-5-benzoylphenyl)acetic acid

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:255.08954328
Heavy Atom Count:19
Complexity:336

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2=CC(=C(C=C2)N)CC(=O)O

Technology Process of (2-Amino-5-benzoylphenyl)acetic acid

There total 5 articles about (2-Amino-5-benzoylphenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 51135-39-8
5-benzoylindolin-2-one

: 51579-81-8
2-amino-5 benzoyl-phenylacetic acid

Guidance literature:: With sodium hydroxide; for 5h; Heating;
DOI:10.1021/jm00377a001

Reference yield:

: 1137-41-3,444317-48-0
(4-aminophenyl)(phenyl)methanone

: 51579-81-8
2-amino-5 benzoyl-phenylacetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: tert-butyl hypochlorite / CH₂Cl₂ / 1 h / -70 °C

2: Et₃N / CH₂Cl₂ / -70 - 20 °C

3: 73 percent / Raney nickel / tetrahydrofuran / 0.17 h

4: 85 percent / 3N aq. NaOH / 5 h / Heating

With sodium hydroxide; tert-butylhypochlorite; nickel; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm00377a001

Reference yield:

: (2-Amino-5-benzoyl-phenyl)-methylsulfanyl-acetic acid ethyl ester

: 51579-81-8
2-amino-5 benzoyl-phenylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / Raney nickel / tetrahydrofuran / 0.17 h

2: 85 percent / 3N aq. NaOH / 5 h / Heating

With sodium hydroxide; nickel; In tetrahydrofuran;
DOI:10.1021/jm00377a001