5,7-Dimethyl-2-[(4-methylbenzyl)thio][1,2,4]triazolo[1,5-a]pyrimidine

Base Information

Chemical Name:5,7-Dimethyl-2-[(4-methylbenzyl)thio][1,2,4]triazolo[1,5-a]pyrimidine
CAS No.:51646-23-2
Molecular Formula:C15H16N4S
Molecular Weight:284.385
Hs Code.:
DSSTox Substance ID:DTXSID001322245
ChEMBL ID:CHEMBL136008

Synonyms:5,7-dimethyl-2-[(4-methylbenzyl)thio][1,2,4]triazolo[1,5-a]pyrimidine;51646-23-2;MLS001000514;CHEMBL136008;DTXSID001322245;HMS2842J04;STK953732;AKOS001347640;5,7-dimethyl-2-[(4-methylphenyl)methylsulfanyl]-[1,2,4]triazolo[1,5-a]pyrimidine;SMR000498354;SR-01000582255;SR-01000582255-1;Z14484386;5,7-dimethyl-2-[(4-methylbenzyl)sulfanyl][1,2,4]triazolo[1,5-a]pyrimidine

Suppliers and Price of 5,7-Dimethyl-2-[(4-methylbenzyl)thio][1,2,4]triazolo[1,5-a]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5,7-Dimethyl-2-[(4-methylbenzyl)thio][1,2,4]triazolo[1,5-a]pyrimidine

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:284.10956770
Heavy Atom Count:20
Complexity:319

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)CSC2=NN3C(=CC(=NC3=N2)C)C

Technology Process of 5,7-Dimethyl-2-[(4-methylbenzyl)thio][1,2,4]triazolo[1,5-a]pyrimidine

There total 3 articles about 5,7-Dimethyl-2-[(4-methylbenzyl)thio][1,2,4]triazolo[1,5-a]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 104-82-5
4-Methylbenzyl chloride

: 51646-17-4
5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-thiol

: 51646-23-2
5,7-dimethyl-2-(4-methyl-benzylsulfanyl)-[1,2,4]triazolo[1,5-a]pyrimidine

Guidance literature:: With sodium hydroxide; In methanol; at 25 ℃;
DOI:10.1021/jm00346a017

Reference yield:

: 123-54-6,81235-32-7
acetylacetone

: 51646-23-2
5,7-dimethyl-2-(4-methyl-benzylsulfanyl)-[1,2,4]triazolo[1,5-a]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid, piperidine / 10 h / Heating

2: 95 percent / 20percent aq. NaOH / methanol / 25 °C

With piperidine; sodium hydroxide; acetic acid; In methanol;
DOI:10.1021/jm00346a017