5-Thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid, 7-amino-3-methylene-8-oxo-, (2R,6R,7R)-

Base Information

Chemical Name:5-Thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid, 7-amino-3-methylene-8-oxo-, (2R,6R,7R)-
CAS No.:51795-31-4
Molecular Formula:C8H10N2O3S
Molecular Weight:214.245
Hs Code.:
Mol file:51795-31-4.mol

Synonyms:(4R,6R,7R)-7-amino-3-methylenecepham-4-carboxylic acid;7β-amino-3-methylene-cepham-4α-carboxylic acid;7-Amino-3-methylencepham-4-carboxylsaeure;(6R)-7t-amino-3-methylene-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]octane-2c-carboxylic acid;

Suppliers and Price of 5-Thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid, 7-amino-3-methylene-8-oxo-, (2R,6R,7R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5-Thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid, 7-amino-3-methylene-8-oxo-, (2R,6R,7R)-

Chemical Property:

Melting Point:None °C
PSA：108.93000
LogP:-0.12360

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid, 7-amino-3-methylene-8-oxo-, (2R,6R,7R)-

There total 1 articles about 5-Thia-1-azabicyclo[4.2.0]octane-2-carboxylic acid, 7-amino-3-methylene-8-oxo-, (2R,6R,7R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 30246-33-4
7-amino-3-(5'-methyl-1',3',4'-thiadiazol-2'-ylthiomethyl)cephalosporanic acid

: 36996-01-7,51795-31-4
7-amino-3-methylenecepham-4-carboxylic acid

: 26395-99-3
7-aminodesacetoxycephalosporanic acid

Guidance literature:: With N,N-Bis(trimethylsilyl)urea; ammonium chloride; zinc; In N,N-dimethyl-formamide; 1.) 25 deg C, 13 min, 2.) 5 deg C, 18 min, 3.) 5 deg C, 30 min;
DOI:10.1248/cpb.36.582

Reference yield:

: 51795-31-4
(6R,7R)-7-amino-3-methylenecepham-4-carboxylic acid

: 15686-71-2,27726-35-8,34632-04-7,79814-91-8,108260-04-4
cefalexin

Guidance literature:: Multi-step reaction with 2 steps

1: (i) ClSiMe₃, PhNMe₂, CH₂Cl₂, (ii) /BRN= 5405183/

2: ClSiMe₃, Py

With pyridine; chloro-trimethyl-silane;

Reference yield:

: 36996-01-7,51795-31-4
7-amino-3-methylenecepham-4-carboxylic acid

: 68403-70-3,115889-60-6
7-amino-3-hydroxycepham-4-carboxylic acid

Guidance literature:: With sodium hydroxide; sodium tetrahydroborate; methanesulfonic acid; ozone; Yield given. Multistep reaction; 1.) MeOH, -75 deg C, 2.) MeOH/H₂O, 0 - 10 deg C;
DOI:10.1248/cpb.36.582