2-(2-Fluorophenyl)-5-methyl-1,3-oxazole-4-carbonyl chloride

Base Information

Chemical Name:2-(2-Fluorophenyl)-5-methyl-1,3-oxazole-4-carbonyl chloride
CAS No.:52169-88-7
Molecular Formula:C₁₁H₇ClFNO₂
Molecular Weight:239.633
Hs Code.:
DSSTox Substance ID:DTXSID70484075
Wikidata:Q82322080
Mol file:52169-88-7.mol

Synonyms:52169-88-7;2-(2-Fluorophenyl)-5-methyloxazole-4-carbonyl chloride;2-(2-Fluorophenyl)-5-methyl-1,3-oxazole-4-carbonyl chloride;SCHEMBL11626894;DTXSID70484075

Suppliers and Price of 2-(2-Fluorophenyl)-5-methyl-1,3-oxazole-4-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-(2-Fluorophenyl)-5-methyl-1,3-oxazole-4-carbonyl chloride

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:239.0149343
Heavy Atom Count:16
Complexity:277

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N=C(O1)C2=CC=CC=C2F)C(=O)Cl

Technology Process of 2-(2-Fluorophenyl)-5-methyl-1,3-oxazole-4-carbonyl chloride

There total 4 articles about 2-(2-Fluorophenyl)-5-methyl-1,3-oxazole-4-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61152-01-0
2-(2-fluoro-phenyl)-5-methyl-oxazole-4-carboxylic acid

: 52169-88-7
2-(2-fluoro-phenyl)-5-methyl-oxazole-4-carbonyl chloride

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide;

Reference yield:

: 61151-91-5
2-(4-chloro-benzoylamino)-3-oxo-butyric acid ethyl ester

: 52169-88-7
2-(2-fluoro-phenyl)-5-methyl-oxazole-4-carbonyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃ / benzene / Heating

2: NaOH / ethanol

3: SOCl₂ / dimethylformamide

With sodium hydroxide; thionyl chloride; trichlorophosphate; In ethanol; N,N-dimethyl-formamide; benzene;

Reference yield:

: 122-01-0
4-chloro-benzoyl chloride

: 52169-88-7
2-(2-fluoro-phenyl)-5-methyl-oxazole-4-carbonyl chloride

Guidance literature:: Multi-step reaction with 4 steps

1: (i) Zn, aq. H₂SO₄, (ii) /BRN= 471606/

2: POCl₃ / benzene / Heating

3: NaOH / ethanol

4: SOCl₂ / dimethylformamide

With sodium hydroxide; thionyl chloride; trichlorophosphate; In ethanol; N,N-dimethyl-formamide; benzene;