Methyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate

Base Information

Chemical Name:Methyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate
CAS No.:52506-21-5
Molecular Formula:C10H14O5
Molecular Weight:214.218
Hs Code.:2932999099
European Community (EC) Number:812-162-7
DSSTox Substance ID:DTXSID50399173
Nikkaji Number:J2.777.065G
Mol file:52506-21-5.mol

Synonyms:methyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate;52506-21-5;SCHEMBL1528558;DTXSID50399173;HDBHPQJOSZBECI-UHFFFAOYSA-N;8-Oxo-1,4-dioxaspiro[4.5]decane-7-carboxylic acid methyl ester;CCA50621;MFCD03271523;AKOS025395939;PS-11233;CS-0215031;EN300-215474;F18118;A870968;AN-907/40847994;methyl8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate;Methyl 8-oxo-1,4-dioxa-spiro[4.5]decane-7-carboxylate;Z1618010753

Suppliers and Price of Methyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
methyl8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate
1g
$ 330.00

SynQuest Laboratories
Methyl8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate
250 mg
$ 128.00

SynQuest Laboratories
Methyl8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate
1 g
$ 376.00

Crysdot
Methyl8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate 95+%
1g
$ 370.00

Chemenu
Methyl8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate 95%
1g
$ 346.00

Apolloscientific
Methyl8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate 96%
1g
$ 341.00

Apolloscientific
Methyl8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate 96%
250mg
$ 116.00

Alichem
Methyl8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate
1g
$ 362.60

Total 13 raw suppliers

Chemical Property of Methyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate

Chemical Property:

PSA：61.83000
LogP:0.27170
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:214.08412354
Heavy Atom Count:15
Complexity:280

Purity/Quality:

97% ^*data from raw suppliers

methyl8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1CC2(CCC1=O)OCCO2

Technology Process of Methyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate

There total 4 articles about Methyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 4746-97-8
cyclohexanedione monoethylene ketal

: 616-38-6
carbonic acid dimethyl ester

: 52506-21-5
8-oxo-1,4-dioxa-spiro[4.5]decane-7-carboxylic acid methyl ester

Guidance literature:: With sodium hydride; for 4h; Reflux;
DOI:10.1021/acs.jmedchem.6b01132

Reference yield: 65.0%

: methyl cyanoformate

: 4746-97-8
cyclohexanedione monoethylene ketal

: 52506-21-5
8-oxo-1,4-dioxa-spiro[4.5]decane-7-carboxylic acid methyl ester

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide; In tetrahydrofuran; at 0 ℃; for 1h;
DOI:10.1002/ejoc.200700336