1,3-Benzenedicarboxylic acid, 5,5'-[1,3-propanediylbis(oxy)]bis-, tetramethyl ester

Base Information

• Chemical Name: 1,3-Benzenedicarboxylic acid, 5,5'-[1,3-propanediylbis(oxy)]bis-, tetramethyl ester
• CAS No.: 52777-57-8
• Molecular Formula: C23H24O10
• Molecular Weight: 460.438
• Mol file: 52777-57-8.mol

Synonyms:

Chemical Property of 1,3-Benzenedicarboxylic acid, 5,5'-[1,3-propanediylbis(oxy)]bis-, tetramethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-Benzenedicarboxylic acid, 5,5'-[1,3-propanediylbis(oxy)]bis-, tetramethyl ester

There total 1 articles about 1,3-Benzenedicarboxylic acid, 5,5'-[1,3-propanediylbis(oxy)]bis-, tetramethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

Dimethyl 5-hydroxyisophthalate (13036-02-7) + 1,3-dibromo-propane (109-64-8) → 1,3-bis-[3,5-bis(methoxycarbonyl)phenoxy]propane (52777-57-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 45h;

DOI:10.1002/1521-3765(20020301)8:5<1227::AID-CHEM1227>3.0.CO;2-0

Reference yield: 95.0%

1,3-bis-[3,5-bis(methoxycarbonyl)phenoxy]propane (52777-57-8) → 5,5′-(propanen-1,3-diyl)-bisoxydiisophthalic acid (433216-78-5)

Guidance literature:

With sodium hydroxide; In ethanol; at 65 ℃; for 12h;

DOI:10.1002/1521-3765(20020301)8:5<1227::AID-CHEM1227>3.0.CO;2-0

Reference yield:

1,3-bis-[3,5-bis(methoxycarbonyl)phenoxy]propane (52777-57-8) → C19H12Cl4O6

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / aq. NaOH / ethanol / 12 h / 65 °C

2: SO₂Cl / dimethylformamide / 14 h / Heating

With sodium hydroxide; sulfuryl dichloride; In ethanol; N,N-dimethyl-formamide;

DOI:10.1002/1521-3765(20020301)8:5<1227::AID-CHEM1227>3.0.CO;2-0

upstream raw materials:

Dimethyl 5-hydroxyisophthalate

1,3-dibromo-propane

Downstream raw materials:

5,5′-(propanen-1,3-diyl)-bisoxydiisophthalic acid

Refernces