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1,3-Dibromopropane

Base Information Edit
  • Chemical Name:1,3-Dibromopropane
  • CAS No.:109-64-8
  • Deprecated CAS:625084-38-0
  • Molecular Formula:C3H6Br2
  • Molecular Weight:201.889
  • Hs Code.:2909.30
  • European Community (EC) Number:203-690-3,686-104-2
  • NSC Number:62663
  • UNII:YQR3048IX9
  • DSSTox Substance ID:DTXSID1021902
  • Nikkaji Number:J2.433C
  • Wikipedia:1,3-Dibromopropane
  • Wikidata:Q408240
  • Mol file:109-64-8.mol
1,3-Dibromopropane

Synonyms:1,3-dibromopropane

Suppliers and Price of 1,3-Dibromopropane
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • AHH
  • 1,3-Dibromopropane 98%
  • 5000g
  • $ 432.00
  • AK Scientific
  • 1,3-Dibromopropane
  • 500g
  • $ 180.00
  • AK Scientific
  • 1,3-Dibromopropane
  • 100g
  • $ 101.00
  • AK Scientific
  • 1,3-Dibromopropane
  • 5g
  • $ 10.00
  • AK Scientific
  • 1,3-Dibromopropane
  • 100g
  • $ 49.00
  • Alfa Aesar
  • 1,3-Dibromopropane, 98%
  • 250g
  • $ 57.40
  • Alfa Aesar
  • 1,3-Dibromopropane, 98%
  • 1000g
  • $ 169.00
  • Alfa Aesar
  • 1,3-Dibromopropane, 98%
  • 5000g
  • $ 739.00
  • Apolloscientific
  • 1,3-Dibromopropane
  • 100ml
  • $ 61.00
  • Apolloscientific
  • 1,3-Dibromopropane
  • 25ml
  • $ 29.00
Total 191 raw suppliers
Chemical Property of 1,3-Dibromopropane Edit
Chemical Property:
  • Appearance/Colour:colourless to slightly yellow liquid 
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:-34 °C(lit.) 
  • Refractive Index:n20/D 1.524(lit.)  
  • Boiling Point:167 °C at 760 mmHg 
  • Flash Point:54.4 °C 
  • PSA:0.00000 
  • Density:1.933 g/cm3 
  • LogP:2.16630 
  • Storage Temp.:2-8°C 
  • Solubility.:1.68g/l 
  • Water Solubility.:1.7 g/L (30 ºC) 
  • XLogP3:2.4
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:0
  • Rotatable Bond Count:2
  • Exact Mass:201.88158
  • Heavy Atom Count:5
  • Complexity:12.4
Purity/Quality:

99.2% *data from raw suppliers

1,3-Dibromopropane 98% *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xn,N,Xi 
  • Statements: 10-22-38-51/53-36/37/38 
  • Safety Statements: 16-26-36-61-24/25 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Chemical Classes:Other Classes -> Halogenated Aliphatics, Saturated
  • Canonical SMILES:C(CBr)CBr
  • Uses 1,3-Dibromopropane is used to prepare C3-bridged compounds through C-N coupling reactions. It is used in the preparation of 2,3,4,5-tetrahydro-7,7-diphenylimidazo- [2,1-b]-thiazine-6(7H)-one by reacting with potassium salt of 5,5-diphenyl-2-thiohydantoin.
Technology Process of 1,3-Dibromopropane

There total 46 articles about 1,3-Dibromopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With Tri-n-butylfluorphosphoniumbromid; In benzene; at 20 ℃; for 24h;
DOI:10.1055/s-1982-29802
Guidance literature:
at 220 ℃; Ausschluss von Licht;
DOI:10.1021/ja01268a506
Guidance literature:
beim Erhitzen;
Refernces Edit

Proline derived spirobarbiturates as highly effective β-turn mimetics incorporating polar and functionalizable constraint elements

10.1021/jo702573z

The study focuses on the synthesis and structural characterization of novel spirobarbiturates as effective β-turn mimetics, which are important for molecular recognition and signal transduction. The researchers synthesized spirobarbiturates of type III using N-carbamoyl-substituted amino acids and pyrrolidine-1,2,2-tricarboxylic acid derivatives through cyclocondensation reactions. Key chemicals used in the study included N-Boc-protected diethylaminomalonate, 1,3-dibromopropane, and various urea derivatives (e.g., N-carbamoyl glycine, phenylalanine, and tyrosine), which served as building blocks in the synthesis process. The introduction of these compounds aimed to create molecular scaffolds that could be utilized as biomolecular probes to explore binding interactions with target proteins, ultimately contributing to the development of peptide mimetics with potential therapeutic applications.

Synthesis of 5 acetoxy 9 oxotridecanolactone. A model for erythronolide B

10.1016/S0040-4039(01)91879-9

The study details the synthesis of 5-acetoxy-9-oxotridecanolactone as a model for erythronolide B, the aglycone of erythromycin B. The researchers aimed to develop a route to 5-acetoxy-13-hydroxy-9-oxotridecanoic acid, with the intention of lactonization at the final stage of macrolide synthesis. The synthesis involved assembling a thirteen-carbon backbone from two cyclopentanoid and one propanoid unit. Key steps included alkylation of the potassio salt of cyclopentanone carboxylic ester with 1,3-dibromopropane, decarboxylation with HBr, Baeyer-Villiger oxidation using CF3CO3H, and further alkylation and decarboxylation steps. The study also involved protecting and unmasking the cyclopentanone carbonyl group, reduction of an ester group with LiAlH4, and oxidation with Collins' reagent. The final lactonization was achieved using p-toluenesulfonyl chloride and Et3N, or alternatively, 1,1'-carbonyldiimidazole and sodium t-amylate. The synthetic route demonstrated potential applicability to erythronolide and other macrolide systems.

Facile syntheses of 4-(2-cyanoethylthio)-1,3-dithiole-2-thione and new electron donors with two TTF units and compounds with bis(1,3-dithiole-2-thione) groups

10.1055/s-2002-34837

The research presents a facile and efficient approach to synthesize 4-(2-cyanoethylthio)-1,3-dithiole-2-thione (1), a key compound for the preparation of tetrathiafulvalene (TTF) derivatives, from TBA2[Zn(dmit)2]. The study explores the synthetic conditions for preparing compound 1 and uses it to synthesize new electron donors with two TTF units. The chemicals used in the process include TBA2[Zn(dmit)2], 3-bromopropionitrile, pyridine hydrochloride, Hg(OAc)2, and various electrophilic reagents such as 1,2-dibromoethane and 1,3-dibromopropane. The research concludes that compound 1 can be synthesized with high efficiency using four equivalents of an organic ammonium salt, yielding new electron donors with two TTF units, which are significant for the study of organic conductors and molecular spin-ladder systems.

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