2-HYDROXY-4'-METHOXYCHALCONE

Base Information

• Chemical Name: 2-HYDROXY-4'-METHOXYCHALCONE
• CAS No.: 52923-29-2
• Molecular Formula: C₁₆H₁₄O₃
• Molecular Weight: 254.285
• Mol file: 52923-29-2.mol

Synonyms:

Chemical Property of 2-HYDROXY-4'-METHOXYCHALCONE

Chemical Property:

• PSA: 46.53000
• LogP: 3.29690

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-HYDROXY-4'-METHOXYCHALCONE

There total 31 articles about 2-HYDROXY-4'-METHOXYCHALCONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C19H20O3 → (E)-1-(2-hydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one (39273-61-5,52923-29-2)

Guidance literature:

With boron trichloride; In dichloromethane; at 0 ℃;

DOI:10.3390/molecules23071620

Reference yield: 94.0%

methyl bromide (74-83-9) + 2',4'-dihydroxychalcone (1776-30-3,25515-43-9) → 1-(2-hydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one (52923-29-2,39273-61-5)

Guidance literature:

With potassium carbonate; In acetone; at 25 - 30 ℃; Irradiation;

DOI:10.1016/j.fct.2021.111969

Reference yield: 86.8%

1-(2-hydroxy-4-methoxyphenyl)ethanone (552-41-0) + benzaldehyde (100-52-7) → 1-(2-hydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one (52923-29-2,39273-61-5)

Guidance literature:

With potassium hydroxide; In methanol; for 4h; Reflux;

DOI:10.1016/j.bmc.2018.10.045

upstream raw materials:

2',4'-dimethoxychalcone

1-(2-hydroxy-4-methoxyphenyl)ethanone

benzaldehyde

O-methylresorcine

Downstream raw materials:

(E)-1-(4-Methoxy-2-{5-methoxy-2-[(E)-(3-phenyl-acryloyl)]-phenoxymethoxy}-phenyl)-3-phenyl-propenone

2',4'-dihydroxychalcone

7-methoxyflavonol

7-methoxyflavanone

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