1-Bromo-2-ethenyl-4,5-dimethoxybenzene

Base Information

Chemical Name:1-Bromo-2-ethenyl-4,5-dimethoxybenzene
CAS No.:5293-43-6
Molecular Formula:C10H11BrO2
Molecular Weight:243.1
Hs Code.:
DSSTox Substance ID:DTXSID80363802
Nikkaji Number:J2.190.309D
Wikidata:Q82147536
Mol file:5293-43-6.mol

Synonyms:1-bromo-2-ethenyl-4,5-dimethoxybenzene;5293-43-6;Benzene, 1-bromo-2-ethenyl-4,5-dimethoxy-;2-Bromo-4,5-dimethoxystyrene;DTXSID80363802;AKOS013992631;EN300-705441

Suppliers and Price of 1-Bromo-2-ethenyl-4,5-dimethoxybenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-Bromo-2-ethenyl-4,5-dimethoxybenzene

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:241.99424
Heavy Atom Count:13
Complexity:172

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C(=C1)C=C)Br)OC

Technology Process of 1-Bromo-2-ethenyl-4,5-dimethoxybenzene

There total 8 articles about 1-Bromo-2-ethenyl-4,5-dimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 5392-10-9
2-bromo-4,5-dimethoxybenzaldehyde

: 2065-66-9
methyl-triphenylphosphonium iodide

: 5293-43-6
1-bromo-4,5-dimethoxy-2-vinylbenzene

Guidance literature:: methyl-triphenylphosphonium iodide; With n-butyllithium; In tetrahydrofuran; at 20 ℃; for 0.333333h; Inert atmosphere;

2-bromo-4,5-dimethoxybenzaldehyde; In tetrahydrofuran; at 20 ℃; for 2h; stereoselective reaction; Inert atmosphere;
DOI:10.1039/c8ob01148f

Reference yield:

: 5392-10-9
2-bromo-4,5-dimethoxybenzaldehyde

: 1779-49-3
Methyltriphenylphosphonium bromide

: 5293-43-6
1-bromo-4,5-dimethoxy-2-vinylbenzene

: 791-28-6
Triphenylphosphine oxide

Guidance literature:: Methyltriphenylphosphonium bromide; With n-butyllithium; In hexane; at -78 - 20 ℃; Inert atmosphere;

2-bromo-4,5-dimethoxybenzaldehyde; In hexane; at -78 - 20 ℃; for 18h; Inert atmosphere;
DOI:10.1021/jo402616w

Reference yield:

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 5293-43-6
1-bromo-4,5-dimethoxy-2-vinylbenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: bromine / methanol / 3 h / 20 °C

2.1: nBuLi / hexane; tetrahydrofuran / 0.25 h / 20 °C

2.2: 0.54 g / hexane; tetrahydrofuran / 3 h / 20 °C

With n-butyllithium; bromine; In tetrahydrofuran; methanol; hexane; 2.1: Wittig olefination;
DOI:10.1002/chem.200700177