2-Formyl-6-methoxybenzoic acid

Base Information

Chemical Name:2-Formyl-6-methoxybenzoic acid
CAS No.:53015-08-0
Molecular Formula:C9H8O4
Molecular Weight:180.16
Hs Code.:
DSSTox Substance ID:DTXSID00399284
Nikkaji Number:J2.287.149H
Wikidata:Q82201721
Mol file:53015-08-0.mol

Synonyms:2-formyl-6-methoxybenzoic acid;53015-08-0;6-methoxyphthalaldehydic acid;2-formyl-6-methoxybenzoicacid;2-Methoxy-6-formylbenzoic acid;SCHEMBL11739432;DTXSID00399284;CFKGGYABZGKDEO-UHFFFAOYSA-N;MFCD04037449;AKOS006277015;AB15372;AS-44601;CS-0141829

Suppliers and Price of 2-Formyl-6-methoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-formyl-6-methoxybenzoicacid
100mg
$ 310.00

TRC
2-formyl-6-methoxybenzoicacid
10mg
$ 45.00

Total 4 raw suppliers

Chemical Property of 2-Formyl-6-methoxybenzoic acid

Chemical Property:

Melting Point:152-153 °C
Boiling Point:352.5±27.0 °C(Predicted)
PKA:4.46±0.10(Predicted)
PSA：63.60000
Density:1.309±0.06 g/cm3(Predicted)
LogP:1.20590
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:180.04225873
Heavy Atom Count:13
Complexity:202

Purity/Quality:

99% ^*data from raw suppliers

2-formyl-6-methoxybenzoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1C(=O)O)C=O

Technology Process of 2-Formyl-6-methoxybenzoic acid

There total 15 articles about 2-Formyl-6-methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70946-17-7
N,N-diethyl-2-formyl-6-methoxybenzamide

: 53015-08-0
2-formyl-6-methoxy-benzoic acid

: 73274-87-0,73713-38-9
3-hydroxy-7-methoxy-3H-isobenzofuran-1-one

Guidance literature:: With hydrogenchloride; water; acetic acid; for 12h; Overall yield = 98 %; Reflux;
DOI:10.1016/j.bmcl.2013.01.074

Reference yield:

: 28281-58-5
7-methoxyisobenzofuran-1(3H)-one

: 53015-08-0
2-formyl-6-methoxy-benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

2: CrO₃; acetic acid / anschliessendes Behandeln mit wss. HCl

With chromium(VI) oxide; acetic acid;

Reference yield:

: 579-75-9
2-Methoxybenzoic acid

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 53015-08-0
2-formyl-6-methoxy-benzoic acid

Guidance literature:: 2-Methoxybenzoic acid; With (E)-N,N,N′,N′-tetramethylethene-1,2-diamine; sec.-butyllithium; In tetrahydrofuran; at -78 ℃; for 2h;

N,N-dimethyl-formamide; In tetrahydrofuran; at -78 - 20 ℃;
DOI:10.1021/ol0530427