4',5,7-Trihydroxyflavan

Base Information

Chemical Name:4',5,7-Trihydroxyflavan
CAS No.:530-82-5
Molecular Formula:C15H14O4
Molecular Weight:258.274
Hs Code.:
ChEMBL ID:CHEMBL471590
DSSTox Substance ID:DTXSID80487431
Nikkaji Number:J2.325.601K
Wikidata:Q82329449
Mol file:530-82-5.mol

Synonyms:4',5,7-trihydroxyflavan;5,7,4'-trihydroxyflavan;530-82-5;CHEMBL471590;SCHEMBL2595111;DTXSID80487431;MDDPZOZWEZNMTK-UHFFFAOYSA-N

Suppliers and Price of 4',5,7-Trihydroxyflavan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4',5,7-Trihydroxyflavan

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:258.08920892
Heavy Atom Count:19
Complexity:301

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC2=C(C=C(C=C2OC1C3=CC=C(C=C3)O)O)O

Technology Process of 4',5,7-Trihydroxyflavan

There total 7 articles about 4',5,7-Trihydroxyflavan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 480-41-1
5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on

: 530-82-5
2-(4-hydroxyphenyl)chromane-5,7-diol

Guidance literature:: With hydrogenchloride; sodium cyanoborohydride; In methanol; for 84h; further solvent;

Reference yield:

: 288-32-4
1H-imidazole

: 18099-45-1
diborane

: 480-41-1
5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on

: 530-82-5
2-(4-hydroxyphenyl)chromane-5,7-diol

Guidance literature:: With sodium borohydrid; sulfuric acid; acetic anhydride; sodium hydrogencarbonate; In tetrahydrofuran; ethanol; water; acetic acid;

Reference yield:

: 895918-06-6
tri-tert-butyl (2-formylbenzene-1,3,5-triyl)tricarbonate

: 530-82-5
2-(4-hydroxyphenyl)chromane-5,7-diol

Guidance literature:: Multi-step reaction with 2 steps

1.1: magnesium bromide dietherate / diethyl ether

1.2: 45 percent / lithium aluminum hydride / diethyl ether / 3 h / -78 - 20 °C

2.1: 75 percent / zinc bromide / CH₂Cl₂ / 6 h / 20 °C

With magnesium dibromide etherate; zinc dibromide; In diethyl ether; dichloromethane;
DOI:10.1016/j.tet.2006.01.109