5-(4-Methoxyphenyl)pyridin-2(1H)-one

Base Information

Chemical Name:5-(4-Methoxyphenyl)pyridin-2(1H)-one
CAS No.:53242-51-6
Molecular Formula:C12H11NO2
Molecular Weight:201.22100
Hs Code.:2933399090
DSSTox Substance ID:DTXSID10602231
Nikkaji Number:J2.861.397K
Wikidata:Q82499203
Mol file:53242-51-6.mol

Synonyms:5-(4-Methoxyphenyl)pyridin-2(1H)-one;53242-51-6;5-(4-METHOXYPHENYL)-1H-PYRIDIN-2-ONE;2-HYDROXY-5-(4-METHOXYPHENYL)PYRIDINE;5-(4-methoxyphenyl)-1,2-dihydropyridin-2-one;SCHEMBL2859085;DTXSID10602231;CHDTWSPLGKBXPY-UHFFFAOYSA-N;MFCD11876650;AKOS015945345;AKOS016007174;DS-2566;FS-3703;5-(4-Methoxyphenyl)pyridine-2(1H)-one;5-(4-methoxyphenyl)-(1H)-pyridin-2-one;DB-332663;CS-0103386;A870788;A1-33908

Suppliers and Price of 5-(4-Methoxyphenyl)pyridin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-(4-Methoxyphenyl)pyridin-2(1H)-one 95+%
1g
$ 242.00

Crysdot
5-(4-Methoxyphenyl)pyridin-2(1H)-one 95+%
5g
$ 921.00

American Custom Chemicals Corporation
5-(4-METHOXYPHENYL)PYRIDIN-2(1H)-ONE 95.00%
5MG
$ 496.42

Ambeed
5-(4-Methoxyphenyl)pyridin-2(1H)-one 95+%
1g
$ 310.00

Alichem
5-(4-Methoxyphenyl)pyridin-2(1H)-one
5g
$ 1246.41

Alichem
5-(4-Methoxyphenyl)pyridin-2(1H)-one
250mg
$ 183.12

AK Scientific
5-(4-Methoxyphenyl)pyridin-2(1H)-one
100mg
$ 132.00

A1 Biochem Labs
5-(4-Methoxyphenyl)pyridin-2(1H)-one 95%
2.5 g
$ 1200.00

Total 20 raw suppliers

Chemical Property of 5-(4-Methoxyphenyl)pyridin-2(1H)-one

Chemical Property:

Melting Point:191 °C (decomp)
Boiling Point:426.2±45.0 °C(Predicted)
PKA:11.83±0.10(Predicted)
PSA：42.35000
Density:1.171±0.06 g/cm3(Predicted)
LogP:2.46280
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:201.078978594
Heavy Atom Count:15
Complexity:299

Purity/Quality:

97% ^*data from raw suppliers

5-(4-Methoxyphenyl)pyridin-2(1H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CNC(=O)C=C2

Technology Process of 5-(4-Methoxyphenyl)pyridin-2(1H)-one

There total 4 articles about 5-(4-Methoxyphenyl)pyridin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 444120-93-8
2-fluoro-5-(4-methoxyphenyl)pyridine

: 53242-51-6
5-(4-methoxyphenyl)pyridin-2(1H)-one

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; for 24h; Heating;
DOI:10.1016/j.bmcl.2007.04.049

Reference yield: 69.0%

: 53242-51-6
5-(4-methoxyphenyl)pyridin-2(1H)-one

Guidance literature:

Reference yield:

: 766-11-0
5-bromo-2-fluoropyridine

: 53242-51-6
5-(4-methoxyphenyl)pyridin-2(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / KOH; n-Bu₄NBr / Pd(PPh₃)4 / tetrahydrofuran / 19 h / Heating

2: 100 percent / aq. HCl / dioxane / 24 h / Heating

With hydrogenchloride; potassium hydroxide; tetrabutylammomium bromide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; 1: Suzuki cross coupling;
DOI:10.1016/j.bmcl.2007.04.049