4-vinyl-dihydrofuran-2(3H)-one

Base Information

• Chemical Name: 4-vinyl-dihydrofuran-2(3H)-one
• CAS No.: 53627-36-4
• Molecular Formula: C₆H₈O₂
• Molecular Weight: 112.128
• Hs Code.: 2932190090
• DSSTox Substance ID: DTXSID90446296
• Nikkaji Number: J801.256C
• Mol file: 53627-36-4.mol

Synonyms:4-vinyl-dihydrofuran-2(3H)-one;53627-36-4;4-ethenyloxolan-2-one;4-vinyldihydrofuran-2(3H)-one;3-vinylbutyrolactone;3-Vinyl-4-butanolide;SCHEMBL895714;DTXSID90446296;AUJAAMXYEHZSLP-UHFFFAOYSA-N;CS-B0698;rac-4-vinyldihydrofuran-2(3h)-one;AKOS037649991;SB46885;CS-14030;FT-0770662;EN300-5020702

Chemical Property of 4-vinyl-dihydrofuran-2(3H)-one

Chemical Property:

• Vapor Pressure: 0.207mmHg at 25°C
• Boiling Point: 209oC at 760 mmHg
• Flash Point: 76.3oC
• PSA: 26.30000
• Density: 1.154g/cm3
• LogP: 0.73550
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 112.052429494
• Heavy Atom Count: 8
• Complexity: 118

Purity/Quality:

97% ^*data from raw suppliers

4-Vinyldihydrofuran-2(3H)-one 98.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C=CC1CC(=O)OC1

Technology Process of 4-vinyl-dihydrofuran-2(3H)-one

There total 14 articles about 4-vinyl-dihydrofuran-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-butoxy-4-vinyl-tetrahydrofuran (82918-78-3) → 3-vinylbutyrolactone (53627-36-4,107022-86-6,107080-45-5,121959-61-3)

Guidance literature:

With jones reagent; In acetone;

DOI:10.1021/ja00384a082

Reference yield: 90.0%

Trimethyl orthoacetate (1445-45-0) + 1,4-diacetoxybut-2-ene (1576-98-3,18621-75-5,25260-60-0) → 3-vinylbutyrolactone (53627-36-4,107022-86-6,107080-45-5,121959-61-3)

Guidance literature:

With di(n-butyl)tin oxide; hydroquinone; at 180 ℃; for 4h; Reagent/catalyst; Temperature; Autoclave;

Reference yield: 89.0%

→ 3-vinylbutyrolactone (53627-36-4,107022-86-6,107080-45-5,121959-61-3)

Guidance literature:

upstream raw materials:

2-butoxy-4-vinyl-tetrahydrofuran

(E)-4-hydroxy-2-butenyl phenyl sulfide

4-(2-vinyloxy-ethoxy)-butan-1-ol

[(Z)-4-(2-Bromo-1-butoxy-ethoxy)-but-2-enylsulfanyl]-benzene

Downstream raw materials:

(3S,4R)-3-(hydroxy(3,4,5-trimethoxyphenyl)methyl)-4-vinyldihydrofuran-2(3H)-one

(1S,3aS,4R,6aR)-1-(2-Benzo[1,3]dioxol-5-yl-7-methoxy-2,3-dihydro-benzo[1,4]dioxin-6-yl)-4-(2,6-dimethoxy-phenoxy)-dihydro-furo[3,4-c]furan-3a-ol

(1S,3aS,4R,6aR)-1-(3-Benzyloxymethyl-7-methoxy-2,3-dihydro-benzo[1,4]dioxin-6-yl)-4-(2,6-dimethoxy-phenoxy)-dihydro-furo[3,4-c]furan-3a-ol

(1S,3aS,4R,6aR)-1-(3-tert-Butoxymethyl-7-methoxy-2,3-dihydro-benzo[1,4]dioxin-6-yl)-4-(2,6-dimethoxy-phenoxy)-dihydro-furo[3,4-c]furan-3a-ol