Cannabisin D

Base Information

• Chemical Name: Cannabisin D
• CAS No.: 144506-19-4
• Molecular Formula: C₃₆H₃₆N₂O₈
• Molecular Weight: 624.69
• Mol file: 144506-19-4.mol

Synonyms:2,3-Naphthalenedicarboxamide,1,2-dihydro-7-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-N,N'-bis[2-(4-hydroxyphenyl)ethyl]-6-methoxy-,(1R,2S)-rel- (9CI); 2,3-Naphthalenedicarboxamide,1,2-dihydro-7-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-N,N'-bis[2-(4-hydroxyphenyl)ethyl]-6-methoxy-,trans-(?à)-; 2,3-Naphthalenedicarboxamide,1,2-dihydro-7-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-N,N'-bis[2-(4-hydroxyphenyl)ethyl]-6-methoxy-,trans-; Cannabisin D

Chemical Property of Cannabisin D

Chemical Property:

• PSA: 157.58000
• LogP: 5.17090

Purity/Quality:

Analysis control,HPLC≥97% ^*data from raw suppliers

CannabisinD ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cannabisin D

There total 9 articles about Cannabisin D which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C40H44N2O8 → (±)-canabisin D (144506-19-4)

Guidance literature:

With trifluorormethanesulfonic acid; at 20 ℃; for 0.25h; Inert atmosphere;

DOI:10.1002/cjoc.201500054

Reference yield: 85.0%

tyramine hydrochloride (60-19-5) + trans-7-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-6-methoxy-1,2-dihydronaphthalene-2,3-dicarboxylic acid → (±)-canabisin D (144506-19-4)

Guidance literature:

trans-7-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-6-methoxy-1,2-dihydronaphthalene-2,3-dicarboxylic acid; With 1-hydroxy-pyrrolidine-2,5-dione; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; for 4h; Cooling with ice;

tyramine hydrochloride; With triethylamine; In acetonitrile; at 20 ℃; for 18h;

DOI:10.1002/ejoc.201301825

Reference yield: 82.0%

C36H34Br2N2O8 → (±)-canabisin D (144506-19-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 50 ℃; for 20h; Inert atmosphere;

DOI:10.1002/cjoc.201500054

upstream raw materials:

tyramine hydrochloride

trans-3-(5-bromo-4-hydroxy-3-methoxyphenyl)-2-propenoic acid

(E)-3-(3-tert-butyl-4-hydroxy-5-methoxyphenyl)-N-(2-(4-hydroxyphenyl)ethyl)-2-propenamide

(E)-N-feruloyltyramine