1-(2-Isopropoxyphenyl)piperazine

Base Information

• Chemical Name: 1-(2-Isopropoxyphenyl)piperazine
• CAS No.: 54013-91-1
• Molecular Formula: C13H20N2O
• Molecular Weight: 220.315
• European Community (EC) Number: 886-569-3
• DSSTox Substance ID: DTXSID40449277
• Nikkaji Number: J1.423.162E
• Wikidata: Q82268695
• ChEMBL ID: CHEMBL9669
• Mol file: 54013-91-1.mol

Synonyms:1-(2-isopropoxyphenyl)piperazine;54013-91-1;1-(2-propan-2-yloxyphenyl)piperazine;1-[2-(propan-2-yloxy)phenyl]piperazine;1-(2-Isopropoxy-phenyl)-piperazine;CHEMBL9669;D0E2FY;2-isopropoxyphenyl piperazine;SCHEMBL3867980;DTXSID40449277;QJULELIONYLITF-UHFFFAOYSA-N;BDBM50017448;1-[2-(methylethoxy)phenyl]piperazine;AKOS010941535;N-[2-(1-methylethoxy)phenyl]piperazine;1-[2-(1-methylethoxy)phenyl]piperazine;PD178845;FT-0741526;EN300-204409

Chemical Property of 1-(2-Isopropoxyphenyl)piperazine

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 220.157563266
• Heavy Atom Count: 16
• Complexity: 202

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)OC1=CC=CC=C1N2CCNCC2

Technology Process of 1-(2-Isopropoxyphenyl)piperazine

There total 5 articles about 1-(2-Isopropoxyphenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-isopropoxyphenyl)piperazine difumarate salt → 2-(1-methylethoxy)phenyl-1-piperazine (54013-91-1)

Guidance literature:

With sodium hydroxide; In dichloromethane; water;

Reference yield:

difumarate 1-(2-isopropoxy-phenyl)-piperazine → 2-(1-methylethoxy)phenyl-1-piperazine (54013-91-1)

Guidance literature:

With sodium hydroxide; In dichloromethane; water;

Reference yield:

fumarate salt of 4-(2-isopropyloxyphenyl)piperazine (119695-87-3) → 2-(1-methylethoxy)phenyl-1-piperazine (54013-91-1)

Guidance literature:

With sodium hydroxide; In water;

upstream raw materials:

piperazine

1-bromo-2-isopropoxybenzene

fumarate salt of 4-(2-isopropyloxyphenyl)piperazine

2-isopropoxy-phenylamine

Downstream raw materials:

1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one

1-[[5-[[4-[2-(1-methylethoxy)phenyl]-1-piperazinyl]methyl]-1H-pyrrol-2-yl]methyl]-2-piperidinone

RWJ 25730

1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-azepan-2-one