4-amino-N-(3,4-dimethylphenyl)benzenesulfonamide

Base Information

• Chemical Name: 4-amino-N-(3,4-dimethylphenyl)benzenesulfonamide
• CAS No.: 20555-67-3
• Molecular Formula: C14H16 N2 O2 S
• Molecular Weight: 276.359
• Hs Code.: 2935009090
• DSSTox Substance ID: DTXSID50354964
• Wikidata: Q82133498
• Mol file: 20555-67-3.mol

Synonyms:4-amino-N-(3,4-dimethylphenyl)benzenesulfonamide;20555-67-3;4-amino-N-(3,4-dimethylphenyl)benzene-1-sulfonamide;Oprea1_444864;Oprea1_607508;SCHEMBL12903520;DTXSID50354964;MFCD02188623;STK085521;AKOS000118569;SB81734;LS-02475;CS-0307891;4-METHYLUMBELLIFERYLSULFATEPOTASSIUMSALT;EN300-09921;AN-329/12896009;SR-01000356247;4-Amino-N-(3,4-dimethylphenyl)-benzenesulfonamide;J-514441;SR-01000356247-1;Benzenesulfonamide, 4-amino-N-(3,4-dimethylphenyl)-;Z56995154

Chemical Property of 4-amino-N-(3,4-dimethylphenyl)benzenesulfonamide

Chemical Property:

• Vapor Pressure: 7.61E-09mmHg at 25°C
• Boiling Point: 465.6°Cat760mmHg
• Flash Point: 235.4°C
• PSA: 80.57000
• Density: 1.295g/cm³
• LogP: 4.42140
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 276.09324893
• Heavy Atom Count: 19
• Complexity: 383

Purity/Quality:

98%min ^*data from raw suppliers

4-Amino-N-(3,4-dimethylphenyl)benzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N)C

Technology Process of 4-amino-N-(3,4-dimethylphenyl)benzenesulfonamide

There total 7 articles about 4-amino-N-(3,4-dimethylphenyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.6%

N-(3,4-dimethylphenyl)-4-nitrobenzenesulfonamide (16937-24-9) → 4-amino-N-(3,4-dimethylphenyl)benzenesulfonamide (20555-67-3)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; under 760.051 Torr;

DOI:10.1021/acs.jmedchem.0c00932

Reference yield: 74.0%

N-(4-(N-(3,4-dimethylphenyl)sulfamoyl)phenyl)acetamide (2158-17-0) → 4-amino-N-(3,4-dimethylphenyl)benzenesulfonamide (20555-67-3)

Guidance literature:

With hydrogenchloride; In methanol; for 0.5h; Heating;

Reference yield:

4-amino-o-xylene (95-64-7) → 4-amino-N-(3,4-dimethylphenyl)benzenesulfonamide (20555-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 4 h / 0 - 20 °C

2: sodium hydroxide / methanol / 3 h / 70 °C

With pyridine; sodium hydroxide; In methanol;

DOI:10.3109/14756366.2011.604851

upstream raw materials:

N-(4-(N-(3,4-dimethylphenyl)sulfamoyl)phenyl)acetamide

4-amino-o-xylene

p-acetylaminobenzenesulfonyl chloride

4-Nitrobenzenesulfonyl chloride

Downstream raw materials:

C₂₁H₂₀N₂O₆S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 20555-67-3 4-AMINO-N-(3,4-DIMETHYLPHENYL)BENZENESULFONAMIDE

Send

Send

Metric Ton KG G Pound L ML

Send

Send