5-Hexynoic acid, 6-phenyl-

Base Information

• Chemical Name: 5-Hexynoic acid, 6-phenyl-
• CAS No.: 540803-87-0
• Molecular Formula: C12H12O2
• Molecular Weight: 188.226
• European Community (EC) Number: 899-225-2
• Nikkaji Number: J2.347.960E

Synonyms:6-phenylhex-5-ynoic acid;5-Hexynoic acid, 6-phenyl-;540803-87-0;SCHEMBL7054026;G53485;EN300-7434781

Chemical Property of 5-Hexynoic acid, 6-phenyl-

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 188.083729621
• Heavy Atom Count: 14
• Complexity: 238

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C#CCCCC(=O)O

Technology Process of 5-Hexynoic acid, 6-phenyl-

There total 10 articles about 5-Hexynoic acid, 6-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methyl 6-phenylhex-5-ynoate (131070-58-1) → 6-phenylhex-5-ynoic acid (540803-87-0)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ja308529n

Reference yield: 93.0%

butyl 6-phenyl-5-hexynoate (1138337-58-2) → 6-phenylhex-5-ynoic acid (540803-87-0)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; at 20 ℃; for 4h;

DOI:10.1002/adsc.201600575

Reference yield: 80.0%

6-phenylhex-5-yn-1-ol (69936-53-4) → 6-phenylhex-5-ynoic acid (540803-87-0)

Guidance literature:

With chromium(VI) oxide; sulfuric acid; water; In acetone; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.200902079

upstream raw materials:

but-3-enoic acid

phenylacetylene

iodobenzene

hex-5-ynoic acid

Downstream raw materials:

6-phenylhex-5-ynoic acid N-(4-methoxyphenyl)amide

(E)-5-styryltetrahydrofuran-2(3H)-one

(3E,5E)-6-phenylhexa-3,5-dienoic acid

7-methoxy-9-phenyl-2,3-dihydro-1H-cyclopentaquinoline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 540803-87-0 5-Hexynoic acid, 6-phenyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send