Benzenesulfonamide, N-[3-(2-bromophenyl)propyl]-4-methyl-

Base Information

Chemical Name:Benzenesulfonamide, N-[3-(2-bromophenyl)propyl]-4-methyl-
CAS No.:543745-59-1
Molecular Formula:C16H18BrNO2S
Molecular Weight:368.294
Hs Code.:
DSSTox Substance ID:DTXSID90466358
Nikkaji Number:J1.856.934E
Wikidata:Q82292909

Synonyms:543745-59-1;Benzenesulfonamide, N-[3-(2-bromophenyl)propyl]-4-methyl-;DTXSID90466358

Suppliers and Price of Benzenesulfonamide, N-[3-(2-bromophenyl)propyl]-4-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzenesulfonamide, N-[3-(2-bromophenyl)propyl]-4-methyl-

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:367.02416
Heavy Atom Count:21
Complexity:399

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NCCCC2=CC=CC=C2Br

Technology Process of Benzenesulfonamide, N-[3-(2-bromophenyl)propyl]-4-methyl-

There total 4 articles about Benzenesulfonamide, N-[3-(2-bromophenyl)propyl]-4-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 65185-60-6
3-(2-bromophenyl)propan-1-amine

: 98-59-9
p-toluenesulfonyl chloride

: 543745-59-1
N-[(4-methylphenyl)sulfonyl]-3-(2-bromophenyl)propylamine

Guidance literature:: With triethylamine; In dichloromethane; for 2h;
DOI:10.1016/0040-4020(96)00266-9

Reference yield:

: 583-55-1
1-Bromo-2-iodobenzene

: 543745-59-1
N-[(4-methylphenyl)sulfonyl]-3-(2-bromophenyl)propylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 99 percent / sodium bicarbonate, tetra-n-butyl ammonium chloride, palladium acetate / dimethylformamide / 48 h / 40 °C

2: 88 percent / NaBH₄ / 1,2-dimethoxy-ethane; methanol / 15 h / 70 °C

3: 84 percent / AlCl₃, LiAlH₄ / diethyl ether / 18 h

4: 65 percent / Et₃N / CH₂Cl₂ / 2 h

With sodium tetrahydroborate; lithium aluminium tetrahydride; aluminium trichloride; tetrabutyl-ammonium chloride; palladium diacetate; sodium hydrogencarbonate; triethylamine; In methanol; 1,2-dimethoxyethane; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0040-4020(96)00266-9

Reference yield:

: 178809-30-8
3-(2-bromo-phenyl)-acrylonitrile

: 543745-59-1
N-[(4-methylphenyl)sulfonyl]-3-(2-bromophenyl)propylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / NaBH₄ / 1,2-dimethoxy-ethane; methanol / 15 h / 70 °C

2: 84 percent / AlCl₃, LiAlH₄ / diethyl ether / 18 h

3: 65 percent / Et₃N / CH₂Cl₂ / 2 h

With sodium tetrahydroborate; lithium aluminium tetrahydride; aluminium trichloride; triethylamine; In methanol; 1,2-dimethoxyethane; diethyl ether; dichloromethane;
DOI:10.1016/0040-4020(96)00266-9