2-(4-Chlorophenyl)-3-phenyl-1,3-thiazolidin-4-one

Base Information

Chemical Name:2-(4-Chlorophenyl)-3-phenyl-1,3-thiazolidin-4-one
CAS No.:54397-10-3
Molecular Formula:C15H12ClNOS
Molecular Weight:289.785
Hs Code.:
DSSTox Substance ID:DTXSID50369710
Nikkaji Number:J499.865K
ChEMBL ID:CHEMBL3780532
Mol file:54397-10-3.mol

Synonyms:2-(4-chlorophenyl)-3-phenyl-1,3-thiazolidin-4-one;54397-10-3;2-(4-chlorophenyl)-3-phenylthiazolidin-4-one;4-Thiazolidinone, 2-(4-chlorophenyl)-3-phenyl-;CHEMBL3780532;DTXSID50369710;CCG-51855;STK952171;AKOS000534644;AKOS016245157;AE-848/08321016;SR-01000423634;SR-01000423634-1;SR-01000423634-2;F0862-0735

Suppliers and Price of 2-(4-Chlorophenyl)-3-phenyl-1,3-thiazolidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(4-Chlorophenyl)-3-phenyl-1,3-thiazolidin-4-one

Chemical Property:

PSA：45.61000
LogP:4.18360
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:289.0328129
Heavy Atom Count:19
Complexity:324

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)N(C(S1)C2=CC=C(C=C2)Cl)C3=CC=CC=C3

Technology Process of 2-(4-Chlorophenyl)-3-phenyl-1,3-thiazolidin-4-one

There total 8 articles about 2-(4-Chlorophenyl)-3-phenyl-1,3-thiazolidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 104-88-1
4-chlorobenzaldehyde

: 68-11-1
mercaptoacetic acid

: 62-53-3
aniline

: 54397-10-3
2-(4-chloro-phenyl)-3-phenyl-thiazolidin-4-one

Guidance literature:: With 1-methyl-3-(3-trialkoxysilylpropyl)-1H-imidazol-3-ium chloride supported on nano Fe₃O₄ coated with SiO₂; at 70 ℃; for 1h;
DOI:10.1016/j.molcata.2014.11.018

Reference yield: 94.0%

: 104-88-1
4-chlorobenzaldehyde

: 68-11-1
mercaptoacetic acid

: 622-37-7
Phenyl azide

: 54397-10-3
2-(4-chloro-phenyl)-3-phenyl-thiazolidin-4-one

Guidance literature:: 4-chlorobenzaldehyde; Phenyl azide; With triphenylphosphine; In neat (no solvent);

mercaptoacetic acid; In neat (no solvent); at 130 ℃; for 0.166667h; Sealed tube; Microwave irradiation;
DOI:10.1002/jhet.1705

Reference yield: 93.0%

: 68-11-1
mercaptoacetic acid

: 2362-79-0
N-(4-chlorobenzylidene)aniline

: 54397-10-3
2-(4-chloro-phenyl)-3-phenyl-thiazolidin-4-one

Guidance literature:: With copper(ll) sulfate pentahydrate; In toluene; at 110 ℃; for 12h; regioselective reaction; Green chemistry;
DOI:10.1016/j.cclet.2015.10.029