Azidobenzene

Base Information

• Chemical Name: Azidobenzene
• CAS No.: 622-37-7
• Molecular Formula: C6H5 N3
• Molecular Weight: 119.126
• European Community (EC) Number: 210-730-3
• NSC Number: 512574
• UNII: 2G0EH7N6YB
• DSSTox Substance ID: DTXSID30878870
• Nikkaji Number: J101.063H
• Wikipedia: Phenyl_azide
• Wikidata: Q1867114
• ChEMBL ID: CHEMBL3236174
• Mol file: 622-37-7.mol

Synonyms:azidobenzene;phenylazide

Chemical Property of Azidobenzene

Chemical Property:

• Melting Point: -27.5°C
• Refractive Index: 1.5589
• Boiling Point: 212.39°C (rough estimate)
• Flash Point: -12°C
• PSA: 49.75000
• Density: 1.0860
• LogP: 2.08116
• Storage Temp.: ?20°C
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 119.048347172
• Heavy Atom Count: 9
• Complexity: 120

Purity/Quality:

99% ^*data from raw suppliers

Azidobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 742248
• Hazard Codes: F,Xn
• Statements: 11-19-48/20/21/22-38
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)N=[N+]=[N-]
• Uses: Phenylazide in greener solvent, 2-methyltetrahydrofuran (2-MeTHF).2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry

Technology Process of Azidobenzene

There total 196 articles about Azidobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl ether (60-29-7,927820-24-4) + aniline (62-53-3) → aniline hydrochloride (142-04-1,36663-09-9) + benzene diazonium chloride (100-34-5) + Phenyl azide (622-37-7)

Guidance literature:

Reference yield:

diethyl ether (60-29-7,927820-24-4) + aniline (62-53-3) → 4-nitro-aniline (100-01-6,104810-17-5) + 2-nitro-aniline (88-74-4) + Phenyl azide (622-37-7)

Guidance literature:

unter Kuehlung;

Reference yield:

cis-nitrous acid (7782-77-6) + phenylhydrazine (100-63-0) → nitrogen(II) oxide (10102-43-9) + Phenyl azide (622-37-7) + dinitrogen monoxide (10024-97-2)

Guidance literature:

byproducts: benzene diazonium salt; react. with 2 mol HNO2;

upstream raw materials:

benzenesulfonamide

benzenediazonium

ethanol

3-acetyl-1,3-diphenyl-triazene

Downstream raw materials:

1-phenyl-3a,4,9,9a-tetrahydro-1H-4,9-epoxido-naphtho[2,3-d][1,2,3]triazole

1,4-diphenyl-1H-1,2,3-triazol-5-amine

(1-phenyl-1H-1,2,3-triazole-4-yl)methanol

(1-phenyl-1H-1,2,3-triazol-5-yl)methanol

Refernces

• 1、 Vignon. "-". . p. 233. Retrieved 1905.
• 2、 Sklorz, Julian A. W.,Hoof, Santina,Rades, Nadine,Derycke, Nicolas,K?ncz?l, Lászl?,Szieberth, Dénes,Weber, Manuela,Wiecko, Jelena,Nyulászi, Lászl?,Hissler, Muriel,Müller, Christian. "Pyridyl-Functionalised 3H-1,2,3,4-Triazaphospholes: Synthesis, Coordination Chemistry and Photophysical Properties of Low-Coordinate Phosphorus Compounds". . p. 11096 - 11109. Retrieved 2015.
• 3、 Aydinli, E.,Cantopcu, E.,Goksu, H.. "Homogeneous catalyst containing Pd in the reduction of aryl azides to primary amines". . . Retrieved 2022/03/17.
• 4、 Proietti, Giampiero,Prathap, Kaniraj Jeya,Ye, Xinchen,Olsson, Richard T.,Dinér, Peter. "Nickel Boride Catalyzed Reductions of Nitro Compounds and Azides: Nanocellulose-Supported Catalysts in Tandem Reactions". supporting information. p. 133 - 146. Retrieved 2021/11/04.