Uridine, 3',5'-dibenzoate

Base Information

• Chemical Name: Uridine, 3',5'-dibenzoate
• CAS No.: 54618-11-0
• Molecular Formula: C23H20N2O8
• Molecular Weight: 452.42
• Mol file: 54618-11-0.mol

Synonyms:3',5'-Di-O-benzoyluridin;3',5'-O-dibenzoyluridine;O3',O5'-dibenzoyl-uridine;((2R,3S,4R,5R)-3-(BENZOYLOXY)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-HYDROXYTETRAHYDROFURAN-2-YL)METHYL BENZOATE;

Chemical Property of Uridine, 3',5'-dibenzoate

Chemical Property:

• PSA: 136.92000
• Density: 1.48±0.1 g/cm3(Predicted)
• LogP: 0.87750

Purity/Quality:

99% ^*data from raw suppliers

((2R,3S,4R,5R)-3-(BENZOYLOXY)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-HYDROXYTETRAHYDROFURAN-2-YL)METHYL BENZOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Uridine, 3',5'-dibenzoate

There total 12 articles about Uridine, 3',5'-dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C36H32N2O9 → 3’,5’-dibenzoyluridine (54618-11-0)

Guidance literature:

With C₁₈H₁₅AuClP*CF₃O₃S^(1-)*Ag⁽¹⁺⁾; In ethanol; dichloromethane; at 20 ℃; for 5h; Inert atmosphere;

DOI:10.1039/c6ra27790j

Reference yield: 82.0%

3',5'-di-O-benzoyl-2'-O-(tert-butyldimethylsilyl)uridine (73793-18-7) → 3',5'-di-O-benzoyluridine (54618-11-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 2h; Ambient temperature;

DOI:10.1021/jo00341a005

Reference yield: 80.0%

tribenzoyl uridine (1748-04-5) → 3’,5’-dibenzoyluridine (54618-11-0)

Guidance literature:

With DOWEX-50W resin; potassium tert-butylate; In tetrahydrofuran; at -50 ℃; for 0.116667h;

DOI:10.1016/S0040-4020(01)87616-X

upstream raw materials:

tribenzoyl uridine

benzoyl chloride

uridine

3’,5’-O-benzoyl-2,2’-anhydrouridine

Downstream raw materials:

C₂₄H₂₂N₂O₈

C₂₄H₂₀N₂O₇

2'-deoxy-2'-fluoro-2'-methyluridine

(2‘R)-2‘-deoxy-2’-fluoro-2-methyluridine-3’,5’-dibenzoate