3'-Cytidylic acid, N-benzoyl-2'-deoxy-, 4-chlorophenyl 2-cyanoethyl ester

Base Information

Chemical Name:3'-Cytidylic acid, N-benzoyl-2'-deoxy-, 4-chlorophenyl 2-cyanoethyl ester
CAS No.:67473-53-4
Molecular Formula:C25H24ClN4O8P
Molecular Weight:574.914
Hs Code.:
European Community (EC) Number:266-697-0
DSSTox Substance ID:DTXSID501147925
Nikkaji Number:J310.253J

Synonyms:67473-53-4;3'-Cytidylic acid, N-benzoyl-2'-deoxy-, 4-chlorophenyl 2-cyanoethyl ester;EINECS 266-697-0;RGCMKOROAACGIZ-MRRPNWGVSA-N;DTXSID501147925

Suppliers and Price of 3'-Cytidylic acid, N-benzoyl-2'-deoxy-, 4-chlorophenyl 2-cyanoethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3'-Cytidylic acid, N-benzoyl-2'-deoxy-, 4-chlorophenyl 2-cyanoethyl ester

Chemical Property:

PSA：171.81000
LogP:4.00438
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:11
Exact Mass:574.1020284
Heavy Atom Count:39
Complexity:1030

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)CO)OP(=O)(OCCC#N)OC4=CC=C(C=C4)Cl
Isomeric SMILES:C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)CO)OP(=O)(OCCC#N)OC4=CC=C(C=C4)Cl

Technology Process of 3'-Cytidylic acid, N-benzoyl-2'-deoxy-, 4-chlorophenyl 2-cyanoethyl ester

There total 4 articles about 3'-Cytidylic acid, N-benzoyl-2'-deoxy-, 4-chlorophenyl 2-cyanoethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89480-27-3
Phosphoric acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 2-cyano-ethyl ester

: 67473-53-4
dbzCp(ClPh,CNEt)

Guidance literature:: With trichloroacetic acid; In chloroform; at -20 ℃; for 0.166667h;

Reference yield:

: 57777-87-4
N⁴-benzoyl-5'-O-(p,p'-dimethoxytrityl)deoxycytidine 3'-<(p-chlorophenyl)(β-cyanoethyl)phosphate>

: 67473-53-4
dbzCp(ClPh,CNEt)

Guidance literature:: With benzenesulfonic acid; In methanol; chloroform;

Reference yield:

: 69507-62-6
(p-chlorophenyl) (β-cyanoethyl) phosphorochloridate

: 67473-53-4
dbzCp(ClPh,CNEt)

Guidance literature:: Multi-step reaction with 2 steps

1: 1-methylimidazole / acetonitrile / 2 h / 20 °C

2: 2percent benzenesulfonic acid / CHCl₃; methanol

With 1-methyl-1H-imidazole; benzenesulfonic acid; In methanol; chloroform; acetonitrile;