4-Tert-butyl-2-(2-oxo-2-phenylethyl)-cyclohexanone

Base Information

Chemical Name:4-Tert-butyl-2-(2-oxo-2-phenylethyl)-cyclohexanone
CAS No.:54669-84-0
Molecular Formula:C18H24O2
Molecular Weight:272.387
Hs Code.:
DSSTox Substance ID:DTXSID70483366

Synonyms:4-tert-butyl-2-(2-oxo-2-phenylethyl)-cyclohexanone;54669-84-0;4-(tert-butyl)-2-(2-oxo-2-phenylethyl)-1-cyclohexanone;4-tert-butyl-2-phenacylcyclohexan-1-one;SCHEMBL2993114;DTXSID70483366;OPWJLYPXLLWOHU-UHFFFAOYSA-N;AKOS021982202

Suppliers and Price of 4-Tert-butyl-2-(2-oxo-2-phenylethyl)-cyclohexanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 4-Tert-butyl-2-(2-oxo-2-phenylethyl)-cyclohexanone

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:272.177630004
Heavy Atom Count:20
Complexity:358

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1CCC(=O)C(C1)CC(=O)C2=CC=CC=C2

Technology Process of 4-Tert-butyl-2-(2-oxo-2-phenylethyl)-cyclohexanone

There total 3 articles about 4-Tert-butyl-2-(2-oxo-2-phenylethyl)-cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 4147-00-6
4-tert-butyl-1-(1-pyrrolidinyl)cyclohexene

: 70-11-1
α-bromoacetophenone

: 54669-84-0
4-tert-butyl-2-phenacylcyclohexanone

Guidance literature:: 4-tert-butyl-1-(1-pyrrolidinyl)cyclohexene; α-bromoacetophenone; In N,N-dimethyl-formamide; at 20 ℃; for 10h;

for 11h; Inert atmosphere;
DOI:10.1021/acs.orglett.0c04056

Reference yield:

: 98-53-3
4-tercbutyl-cyclohexanone

: 54669-84-0
4-tert-butyl-2-phenacylcyclohexanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene / 18 h / Molecular sieve; Reflux

2.1: N,N-dimethyl-formamide / 10 h / 20 °C

2.2: 11 h / Inert atmosphere

In N,N-dimethyl-formamide; toluene;
DOI:10.1021/acs.orglett.0c04056